caa a22 4500 46317836X CHVBK 20180406164831.0 cr unu---uuuuu 170326e20070301xx s 000 0 eng 10.1007/s10278-006-0773-7 doi (NATIONALLICENCE)springer-10.1007/s10278-006-0773-7 White Matter Fiber Tracking Computation Based on Diffusion Tensor Imaging for Clinical Applications [Elektronische Daten] [Paulo Dellani, Martin Glaser, Paulo Wille, Goran Vucurevic, Axel Stadie, Thomas Bauermann, Andrei Tropine, Axel Perneczky, Aldo von Wangenheim, Peter Stoeter] Fiber tracking allows the in vivo reconstruction of human brain white matter fiber trajectories based on magnetic resonance diffusion tensor imaging (MR-DTI), but its application in the clinical routine is still in its infancy. In this study, we present a new software for fiber tracking, developed on top of a general-purpose DICOM (digital imaging and communications in medicine) framework, which can be easily integrated into existing picture archiving and communication system (PACS) of radiological institutions. Images combining anatomical information and the localization of different fiber tract trajectories can be encoded and exported in DICOM and Analyze formats, which are valuable resources in the clinical applications of this method. Fiber tracking was implemented based on existing line propagation algorithms, but it includes a heuristic for fiber crossings in the case of disk-shaped diffusion tensors. We successfully performed fiber tracking on MR-DTI data sets from 26 patients with different types of brain lesions affecting the corticospinal tracts. In all cases, the trajectories of the central spinal tract (pyramidal tract) were reconstructed and could be applied at the planning phase of the surgery as well as in intraoperative neuronavigation. SCAR (Society for Computer Applications in Radiology), 2007 Diffusion tensor imaging nationallicence fiber tracking nationallicence pyramidal tract nationallicence cortico-spinal tracts nationallicence neurosurgical planning and navigation nationallicence DICOM nationallicence Dellani Paulo Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut Glaser Martin Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut Wille Paulo Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut Vucurevic Goran Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut Stadie Axel Department of Neurosurgery, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut Bauermann Thomas Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut Tropine Andrei Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut Perneczky Axel Department of Neurosurgery, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut von Wangenheim Aldo Department of Statistics and Computer Sciences, Federal University of Santa Catarina, Santa Catarina, Brazil aut Stoeter Peter Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut Journal of Digital Imaging Springer-Verlag; http://www.springer-ny.com 20/1(2007-03-01), 88-97 0897-1889 20:1<88 2007 20 10278 https://doi.org/10.1007/s10278-006-0773-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10278-006-0773-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dellani Paulo Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut NATIONALLICENCE 700 1- Glaser Martin Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut NATIONALLICENCE 700 1- Wille Paulo Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut NATIONALLICENCE 700 1- Vucurevic Goran Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut NATIONALLICENCE 700 1- Stadie Axel Department of Neurosurgery, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut NATIONALLICENCE 700 1- Bauermann Thomas Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut NATIONALLICENCE 700 1- Tropine Andrei Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut NATIONALLICENCE 700 1- Perneczky Axel Department of Neurosurgery, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut NATIONALLICENCE 700 1- von Wangenheim Aldo Department of Statistics and Computer Sciences, Federal University of Santa Catarina, Santa Catarina, Brazil aut NATIONALLICENCE 700 1- Stoeter Peter Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany aut NATIONALLICENCE 773 0- Journal of Digital Imaging Springer-Verlag; http://www.springer-ny.com 20/1(2007-03-01), 88-97 0897-1889 20:1<88 2007 20 10278 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer