caa a22 4500 463179110 CHVBK 20180406164833.0 cr unu---uuuuu 170326e20070101xx s 000 0 eng 10.1007/s00381-006-0186-4 doi (NATIONALLICENCE)springer-10.1007/s00381-006-0186-4 Evaluation of the lumbar and ventricular infusion test in the diagnostic strategy of pediatric hydrocephalus and the therapeutic implications [Elektronische Daten] [Tina Munch, Rachid Bech-Azeddine, Lars Boegeskov, Flemming Gjerris, Marianne Juhler] Aim: To evaluate the infusion test as a diagnostic tool behind the choice of intervention in pediatric hydrocephalus. Materials and methods: Intracranial pressure (ICP) measurement and infusion test were performed intraventricularly, by lumbar route, or combined in 40 consecutive children as a part of the standard diagnostic program in 1996-1999. Results: The median age was 18.5months, ranging from 2weeks to 13years. In the subgroup of patients with radiological aqueductal stenosis (N=14), mean lumbar/intraventricular ICP was 13 (3-35)/10 (2-27). Mean lumbar/ventricular R out were 18 (4-49)/17 (6-37). For patients with radiological communication between the third and fourth ventricles (N=14), the mean lumbar/intraventricular ICP was 11 (7-17)/9 (1-16). Mean lumbar/ventricular R out were 8 (3-11)/8 (4-12). A total of 13 patients had a shunt insertion, 10 had an endoscopic third ventriculostomy (ETV), 5 had endoscopic fenestration of a cyst, and 12 had no surgery. Of the patients initially treated with EVT, 50% had a shunt insertrion shortly after. For communicating hydrocephalus, 75% of the patients initially not operated based on normal R out values ended up having a shunt insertion. Discussion: R out has doubtful value as an indicator for conducting an operation or not and in the choice between EVT and shunt in chiladren. This should be interpreted in the light of a growing understanding of hydrocephalus on a molecular level. Springer-Verlag, 2006 Children nationallicence CSF circulation nationallicence R out measurement nationallicence Hydrocephalus nationallicence Infusion test nationallicence Munch Tina University Clinic of Neurosurgery, Department 2092, The Neuroscience Centre, Rigshospitalet, 2100, Copenhagen, Denmark aut Bech-Azeddine Rachid University Clinic of Neurosurgery, Department 2092, The Neuroscience Centre, Rigshospitalet, 2100, Copenhagen, Denmark aut Boegeskov Lars University Clinic of Neurosurgery, Department 2092, The Neuroscience Centre, Rigshospitalet, 2100, Copenhagen, Denmark aut Gjerris Flemming University Clinic of Neurosurgery, Department 2092, The Neuroscience Centre, Rigshospitalet, 2100, Copenhagen, Denmark aut Juhler Marianne University Clinic of Neurosurgery, Department 2092, The Neuroscience Centre, Rigshospitalet, 2100, Copenhagen, Denmark aut Child's Nervous System Springer-Verlag 23/1(2007-01-01), 67-71 0256-7040 23:1<67 2007 23 381 https://doi.org/10.1007/s00381-006-0186-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00381-006-0186-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Munch Tina University Clinic of Neurosurgery, Department 2092, The Neuroscience Centre, Rigshospitalet, 2100, Copenhagen, Denmark aut NATIONALLICENCE 700 1- Bech-Azeddine Rachid University Clinic of Neurosurgery, Department 2092, The Neuroscience Centre, Rigshospitalet, 2100, Copenhagen, Denmark aut NATIONALLICENCE 700 1- Boegeskov Lars University Clinic of Neurosurgery, Department 2092, The Neuroscience Centre, Rigshospitalet, 2100, Copenhagen, Denmark aut NATIONALLICENCE 700 1- Gjerris Flemming University Clinic of Neurosurgery, Department 2092, The Neuroscience Centre, Rigshospitalet, 2100, Copenhagen, Denmark aut NATIONALLICENCE 700 1- Juhler Marianne University Clinic of Neurosurgery, Department 2092, The Neuroscience Centre, Rigshospitalet, 2100, Copenhagen, Denmark aut NATIONALLICENCE 773 0- Child's Nervous System Springer-Verlag 23/1(2007-01-01), 67-71 0256-7040 23:1<67 2007 23 381 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer