caa a22 4500 463179536 CHVBK 20180406164834.0 cr unu---uuuuu 170326e20070701xx s 000 0 eng 10.1007/s00381-006-0290-5 doi (NATIONALLICENCE)springer-10.1007/s00381-006-0290-5 Undiagnosed medulloblastoma presenting as fatal hemorrhage in a 14-year-old boy: case report and review of the literature [Elektronische Daten] [Mariarita Santi, Nadja Kadom, Gilbert Vezina, Elisabeth Rushing] Introduction: A 14-year-old boy with no significant medical history presented to the emergency room with a sudden onset of severe headache of 1day's duration. On admission, a non-contrast computed tomography (CT) of the head showed a posterior fossa hemorrhagic mass. Materials and methods: He was immediately intubated and underwent placement of an external drainage tube. A magnetic resonance imaging (MRI) was performed, which showed a large hemorrhagic mass with upward cerebellar herniation. Results: Despite aggressive measures, he deteriorated and was pronounced brain dead 2days after admission. Pathological examination of the mass revealed a medulloblastoma with extensive neuronal and astrocytic differentiation. Conclusion: This case represents one of the few cases of rapid, hemorrhagic expansion associated with a previously undiagnosed medulloblastoma. The topic of hemorrhage due to previously unrecognized brain tumors is discussed and the value of imaging methods used in the diagnostic assessment is emphasized. Springer-Verlag, 2007 Child nationallicence CT nationallicence Hemorrhage nationallicence Medulloblastoma nationallicence MRI nationallicence Santi Mariarita Division of Pathology, Children's National Medical Center, Washington, DC, USA aut Kadom Nadja Division of Radiology, Children's National Medical Center, Washington, DC, USA aut Vezina Gilbert Division of Radiology, Children's National Medical Center, Washington, DC, USA aut Rushing Elisabeth Department of Neuropathology and Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC, USA aut Child's Nervous System Springer-Verlag 23/7(2007-07-01), 799-805 0256-7040 23:7<799 2007 23 381 https://doi.org/10.1007/s00381-006-0290-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00381-006-0290-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Santi Mariarita Division of Pathology, Children's National Medical Center, Washington, DC, USA aut NATIONALLICENCE 700 1- Kadom Nadja Division of Radiology, Children's National Medical Center, Washington, DC, USA aut NATIONALLICENCE 700 1- Vezina Gilbert Division of Radiology, Children's National Medical Center, Washington, DC, USA aut NATIONALLICENCE 700 1- Rushing Elisabeth Department of Neuropathology and Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC, USA aut NATIONALLICENCE 773 0- Child's Nervous System Springer-Verlag 23/7(2007-07-01), 799-805 0256-7040 23:7<799 2007 23 381 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer