caa a22 4500 463179889 CHVBK 20180406164835.0 cr unu---uuuuu 170326e20071201xx s 000 0 eng 10.1007/s00381-007-0470-y doi (NATIONALLICENCE)springer-10.1007/s00381-007-0470-y Effective correction of frontal cranial deformities using biodegradable fixation on the inner surface of the cranial bones during infancy [Elektronische Daten] [Willy Serlo, Leena Ylikontiola, Anna-Liisa Vesala, Outi Kaarela, Tarja Iber, George Sándor, Nureddin Ashammakhi] Purpose: Fixation of cranial bones in pediatric craniofacial surgery with biodegradable materials has developed into an accepted method. However, placing the fixation material on the outer surface of the cranial bone at the frontal cranium in infants can result in suboptimal cosmetic outcomes, as the plates and screws can be palpable. The placement of resorbable fixation devices on the inner surface of the skull would allow for less obvious fixation beneath the skin with a potentially superior cosmetic result. The authors report the use of such resorbable fixation devices on the inner or endocranial aspect of the cranium which appears to be novel. Materials and methods: Ten patients with the mean age of 14months (range 7-35months) were treated with cranial remodeling using poly(lactide-co-glycolide) (PLGA) biodegradable fixation on the inner surface of the cranial bones. Five patients had trigonocephaly, four plagiocephaly, and one brachycephaly. All patients had 3D computed tomography (CT) and clinical photographs done preoperatively and postoperatively at follow-up. The outcome was judged at follow-up by clinical evaluation, photographs, 3D CT, and interview of the parents. The mean follow-up time was 3.5years (range 0.5-6years). Results: The primary recovery was uneventful in all cases. No wound infection occurred, but one patient had a minor skin necrosis which required a single revision operation to correct. The cosmetic outcome was scored as excellent, good, fair, or poor. There was no case with delayed union. Seven out of ten cases were judged as excellent and three as good, none as fair or poor. Conclusions: The use of resorbable PLGA fixation devices on the inner aspect of the skull appears to provide a satisfactory cosmetic result in this small preliminary group of pediatric patients. Further long-term study of these materials in this specific location in a larger patient group is needed. Springer-Verlag, 2007 Biodegradable nationallicence Cranioplasty nationallicence Endocranial nationallicence Serlo Willy Department of Surgery and Paediatrics, Division of Pediatric Surgery, Oulu University, Oulu, Finland aut Ylikontiola Leena Department of Oral and Maxillofacial Surgery, University of Oulu, Oulu, Finland aut Vesala Anna-Liisa Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland aut Kaarela Outi Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland aut Iber Tarja Department of Pediatric Surgery, Tampere University Hospital, Tampere, Finland aut Sándor George Department of Oral and Maxillofacial Surgery, University of Oulu, Oulu, Finland aut Ashammakhi Nureddin Regenerative Medicine, Institute of Science and Technology in Medicine, Keele University, Keele, UK aut Child's Nervous System Springer-Verlag 23/12(2007-12-01), 1439-1445 0256-7040 23:12<1439 2007 23 381 https://doi.org/10.1007/s00381-007-0470-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00381-007-0470-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Serlo Willy Department of Surgery and Paediatrics, Division of Pediatric Surgery, Oulu University, Oulu, Finland aut NATIONALLICENCE 700 1- Ylikontiola Leena Department of Oral and Maxillofacial Surgery, University of Oulu, Oulu, Finland aut NATIONALLICENCE 700 1- Vesala Anna-Liisa Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland aut NATIONALLICENCE 700 1- Kaarela Outi Department of Surgery, Oulu University Hospital, University of Oulu, Oulu, Finland aut NATIONALLICENCE 700 1- Iber Tarja Department of Pediatric Surgery, Tampere University Hospital, Tampere, Finland aut NATIONALLICENCE 700 1- Sándor George Department of Oral and Maxillofacial Surgery, University of Oulu, Oulu, Finland aut NATIONALLICENCE 700 1- Ashammakhi Nureddin Regenerative Medicine, Institute of Science and Technology in Medicine, Keele University, Keele, UK aut NATIONALLICENCE 773 0- Child's Nervous System Springer-Verlag 23/12(2007-12-01), 1439-1445 0256-7040 23:12<1439 2007 23 381 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer