caa a22 4500 46318033X CHVBK 20180406164837.0 cr unu---uuuuu 170326e20070401xx s 000 0 eng 10.1007/s00381-006-0259-4 doi (NATIONALLICENCE)springer-10.1007/s00381-006-0259-4 Mehrazin M. Department of Neurological Surgery, Dr. Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran aut Pituitary tumors in children: clinical analysis of 21 cases [Elektronische Daten] [M. Mehrazin] Objective: The aim of this study is to review the results of surgery for pituitary adenomas in children less than 18years old. Materials and methods: A retrospective review was done of pituitary adenoma patients with the age of less than 18years who were treated in the period 1979-2003 at Dr. Shariati Hospital. Conclusions: Twenty-one patients (12 girls and 9 boys) were identified. The age range (mean) in girls and boys was 9-18 (15.8) and 9-17 (14.8) years, respectively. The duration of follow-up was 1-23 (13.4) years. Eight patients (38.1%) had adrenocorticotropic hormone-secreting tumors, 33.3% had prolactin-secreting tumors, 19% had growth hormone-secreting tumors, and 9.53% had nonfunctioning adenomas. Multidisciplinary management included surgery and, if necessary, reoperation with/without radiotherapy and pharmacotherapy. Eleven patients, mostly with prolactinomas, acromegaly, and nonfunctioning adenomas, needed reoperation and radiotherapy. There were two deaths, one of which was because of apoplexy. The biological behavior of pediatric pituitary adenomas seems more aggressive than adults' adenomas. The chance of pituitary apoplexy in pediatric invasive pituitary adenoma is high. Springer-Verlag, 2006 Children nationallicence Pituitary adenomas nationallicence Clinical analysis nationallicence Pituitary apoplexy nationallicence Child's Nervous System Springer-Verlag 23/4(2007-04-01), 391-398 0256-7040 23:4<391 2007 23 381 https://doi.org/10.1007/s00381-006-0259-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00381-006-0259-4 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Mehrazin M. Department of Neurological Surgery, Dr. Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran aut NATIONALLICENCE 773 0- Child's Nervous System Springer-Verlag 23/4(2007-04-01), 391-398 0256-7040 23:4<391 2007 23 381 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer