caa a22 4500 463180399 CHVBK 20180406164837.0 cr unu---uuuuu 170326e20070401xx s 000 0 eng 10.1007/s00381-006-0262-9 doi (NATIONALLICENCE)springer-10.1007/s00381-006-0262-9 Surgical treatment of polymicrogyria with advanced radiologic and neurophysiologic techniques [Elektronische Daten] [Uğur Işık, Alp Dinçer, Memet Özek] Introduction: Coexistence of multiple seizure types, inclusion of the motor cortex in the epileptogenic zone, and poor delimitation of the abnormal cortex make most patients with polymicrogyria (PMG) unlikely candidates for epilepsy surgery (Guerrini R et al., Epilepsy and malformations of the cerebral cortex in Epileptic syndromes in infancy, childhood and adolescence, 2005). Case report: We present here a child with frontal PMG and intractable epilepsy evaluated with advanced magnetic resonance imaging (MRI) and neurophysiologic techniques. Diffusion tensor imaging and fiber tractography showed severe involvement of neighboring white matter tracts besides the cortex. The evaluation also included functional MRI, chronic subdural electroencephalogram monitoring, and intra-operative motor mapping. The patient had a decrease in seizure frequency and an increase in his developmental skills after the surgery. Conclusion: Advanced neuroradiologic and neurophysiologic techniques are required to provide an effective and safe resection of the epileptogenic cortex in cortical dysplasias. Springer-Verlag, 2006 Children nationallicence Electroencephalography nationallicence Epilepsy nationallicence Diffusion tensor imaging nationallicence Polymicrogyria nationallicence Surgery nationallicence Işık Uğur Division of Pediatric Neurology, Acıbadem Institute of Neurological Sciences, Istanbul, Turkey aut Dinçer Alp Division of Radiology, Acıbadem Institute of Neurological Sciences, Istanbul, Turkey aut Özek Memet Division of Pediatric Neurosurgery, Acıbadem Institute of Neurological Sciences, Istanbul, Turkey aut Child's Nervous System Springer-Verlag 23/4(2007-04-01), 443-448 0256-7040 23:4<443 2007 23 381 https://doi.org/10.1007/s00381-006-0262-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00381-006-0262-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Işık Uğur Division of Pediatric Neurology, Acıbadem Institute of Neurological Sciences, Istanbul, Turkey aut NATIONALLICENCE 700 1- Dinçer Alp Division of Radiology, Acıbadem Institute of Neurological Sciences, Istanbul, Turkey aut NATIONALLICENCE 700 1- Özek Memet Division of Pediatric Neurosurgery, Acıbadem Institute of Neurological Sciences, Istanbul, Turkey aut NATIONALLICENCE 773 0- Child's Nervous System Springer-Verlag 23/4(2007-04-01), 443-448 0256-7040 23:4<443 2007 23 381 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer