caa a22 4500 463181336 CHVBK 20180406164840.0 cr unu---uuuuu 170326e20071101xx s 000 0 eng 10.1007/s00381-007-0391-9 doi (NATIONALLICENCE)springer-10.1007/s00381-007-0391-9 Nonfunctioning endocrine tumor arising from intracranial ectopic pancreas associated with congenital brain malformation [Elektronische Daten] [Hitoshi Tsugu, Shinya Oshiro, Hiroshi Kawaguchi, Takeo Fukushima, Kazuki Nabeshima, Shinji Matsumoto, Yuko Nomura, Sawa Yasumoto, Koichi Takano, Hidetsuna Utsunomiya] Case report: We report a case of a nonfunctioning pancreatic endocrine tumor arising from intracranial ectopic pancreatic tissue. History: An 11-year-old girl was admitted to our hospital with a brain tumor. Hydrocephalus and brain malformation were apparent at birth. We first identified a mass-like lesion in the child's brain at age 4months. We monitored the lesion yearly by magnetic resonance imaging (MRI) until she reached age 11years. Gadolinium-enhanced MRI showed the lesion to be a tumor, which was resected. Pathology: Examination of surgical specimens revealed a mature pancreatic tissue. We also identified monotonous neoplastic cells with round nuclei and positive immunoreactivity for synaptophysin, chromogranin A, and neurospecific enolase. However, these cells were negative for pancreatic endocrine markers. We diagnosed nonfunctioning pancreatic endocrine tumor arising from intracranial ectopic pancreatic tissue. Conclusion: Migrating pancreatic elements may have induced brain malformation during embryonic development and subsequently become malignant. Springer-Verlag, 2007 Congenital brain malformation nationallicence Ectopic pancreas nationallicence Endocrine tumor nationallicence Intracranial nationallicence Pancreas nationallicence Tsugu Hitoshi Department of Neurosurgery, Fukuoka University Faculty of Medicine, 45-1, 7-chome, Nanakuma Jonan-ku, 814-0180, Fukuoka, Japan aut Oshiro Shinya Department of Neurosurgery, Fukuoka University Faculty of Medicine, 45-1, 7-chome, Nanakuma Jonan-ku, 814-0180, Fukuoka, Japan aut Kawaguchi Hiroshi Department of Neurosurgery, Fukuoka University Faculty of Medicine, 45-1, 7-chome, Nanakuma Jonan-ku, 814-0180, Fukuoka, Japan aut Fukushima Takeo Department of Neurosurgery, Fukuoka University Faculty of Medicine, 45-1, 7-chome, Nanakuma Jonan-ku, 814-0180, Fukuoka, Japan aut Nabeshima Kazuki Department of Pathology, Fukuoka University Faculty of Medicine, Fukuoka, Japan aut Matsumoto Shinji Department of Pathology, Fukuoka University Faculty of Medicine, Fukuoka, Japan aut Nomura Yuko Department of Pediatrics, Fukuoka University Faculty of Medicine, Fukuoka, Japan aut Yasumoto Sawa Department of Pediatrics, Fukuoka University Faculty of Medicine, Fukuoka, Japan aut Takano Koichi Department of Radiology, Fukuoka University Faculty of Medicine, Fukuoka, Japan aut Utsunomiya Hidetsuna Department of Radiology, Fukuoka University Faculty of Medicine, Fukuoka, Japan aut Child's Nervous System Springer-Verlag 23/11(2007-11-01), 1337-1340 0256-7040 23:11<1337 2007 23 381 https://doi.org/10.1007/s00381-007-0391-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00381-007-0391-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tsugu Hitoshi Department of Neurosurgery, Fukuoka University Faculty of Medicine, 45-1, 7-chome, Nanakuma Jonan-ku, 814-0180, Fukuoka, Japan aut NATIONALLICENCE 700 1- Oshiro Shinya Department of Neurosurgery, Fukuoka University Faculty of Medicine, 45-1, 7-chome, Nanakuma Jonan-ku, 814-0180, Fukuoka, Japan aut NATIONALLICENCE 700 1- Kawaguchi Hiroshi Department of Neurosurgery, Fukuoka University Faculty of Medicine, 45-1, 7-chome, Nanakuma Jonan-ku, 814-0180, Fukuoka, Japan aut NATIONALLICENCE 700 1- Fukushima Takeo Department of Neurosurgery, Fukuoka University Faculty of Medicine, 45-1, 7-chome, Nanakuma Jonan-ku, 814-0180, Fukuoka, Japan aut NATIONALLICENCE 700 1- Nabeshima Kazuki Department of Pathology, Fukuoka University Faculty of Medicine, Fukuoka, Japan aut NATIONALLICENCE 700 1- Matsumoto Shinji Department of Pathology, Fukuoka University Faculty of Medicine, Fukuoka, Japan aut NATIONALLICENCE 700 1- Nomura Yuko Department of Pediatrics, Fukuoka University Faculty of Medicine, Fukuoka, Japan aut NATIONALLICENCE 700 1- Yasumoto Sawa Department of Pediatrics, Fukuoka University Faculty of Medicine, Fukuoka, Japan aut NATIONALLICENCE 700 1- Takano Koichi Department of Radiology, Fukuoka University Faculty of Medicine, Fukuoka, Japan aut NATIONALLICENCE 700 1- Utsunomiya Hidetsuna Department of Radiology, Fukuoka University Faculty of Medicine, Fukuoka, Japan aut NATIONALLICENCE 773 0- Child's Nervous System Springer-Verlag 23/11(2007-11-01), 1337-1340 0256-7040 23:11<1337 2007 23 381 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer