caa a22 4500 463181360 CHVBK 20180406164840.0 cr unu---uuuuu 170326e20071101xx s 000 0 eng 10.1007/s00381-007-0390-x doi (NATIONALLICENCE)springer-10.1007/s00381-007-0390-x Germinoma with synchronous involvement of midline and off-midline structures associated with progressive hemiparesis and hemiatrophy in a young adult [Elektronische Daten] [S. Sartori, A. Laverda, M. Calderone, C. Carollo, E. Viscardi, R. Faggin, G. Perilongo] Introduction: Cerebral germinomas, the most common and least malignant intracranial germ cell tumors, usually arise in the pineal or suprasellar region and have characteristic clinical and radiological features. Germinomas more rarely occur in the thalamus, basal ganglia, and internal capsule, causing sometimes cerebral hemiatrophy and hemiparesis. More rarely, other clinical features can be fever of unknown origin, visual disturbance, and neuropsychiatric symptoms. Cerebral hemiatrophy can precede the imaging depiction of the off-midline mass. Case: The authors present the first case of cerebral germinoma with synchronous involvement of the midline and off-midline structures, with unusual clinical and radiological presentation. Discussion: The literature is reviewed, and the pathogenesis, the clinical findings, the imaging, and the therapy are discussed. Springer-Verlag, 2007 Basal ganglia nationallicence Germ cell tumor nationallicence Germinoma nationallicence Hemiatrophy nationallicence Hemiparesis nationallicence Magnetic resonance imaging nationallicence Thalamus nationallicence Sartori S. Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128, Padua, Italy aut Laverda A. Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128, Padua, Italy aut Calderone M. Insitute of Neuroradiology, Via Giustiniani 3, 35128, Padua, Italy aut Carollo C. Insitute of Neuroradiology, Via Giustiniani 3, 35128, Padua, Italy aut Viscardi E. Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128, Padua, Italy aut Faggin R. Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128, Padua, Italy aut Perilongo G. Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128, Padua, Italy aut Child's Nervous System Springer-Verlag 23/11(2007-11-01), 1341-1345 0256-7040 23:11<1341 2007 23 381 https://doi.org/10.1007/s00381-007-0390-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00381-007-0390-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sartori S. Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128, Padua, Italy aut NATIONALLICENCE 700 1- Laverda A. Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128, Padua, Italy aut NATIONALLICENCE 700 1- Calderone M. Insitute of Neuroradiology, Via Giustiniani 3, 35128, Padua, Italy aut NATIONALLICENCE 700 1- Carollo C. Insitute of Neuroradiology, Via Giustiniani 3, 35128, Padua, Italy aut NATIONALLICENCE 700 1- Viscardi E. Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128, Padua, Italy aut NATIONALLICENCE 700 1- Faggin R. Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128, Padua, Italy aut NATIONALLICENCE 700 1- Perilongo G. Department of Pediatrics, University of Padua, Via Giustiniani 3, 35128, Padua, Italy aut NATIONALLICENCE 773 0- Child's Nervous System Springer-Verlag 23/11(2007-11-01), 1341-1345 0256-7040 23:11<1341 2007 23 381 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer