caa a22 4500 463184556 CHVBK 20180406164848.0 cr unu---uuuuu 170326e20070301xx s 000 0 eng 10.1007/s10870-006-9159-4 doi (NATIONALLICENCE)springer-10.1007/s10870-006-9159-4 Synthesis, spectroscopic and crystal structure analysis of a compound with pharmocophoric substituent: 2-cyclohexyl-6-(2-oxo-2H-chromen-3-yl)- imidazo[2,1-b][1,3,4]thiadiazole-5-carbaldehyde [Elektronische Daten] [Noor Begum, D. Vasundhara, C. Girija, G. Kolavi, V. Hegde, I. Khazi] Imidazo[2,1-b][1,3,4] thiadiazole derivatives are significant for their various pharmacological properties. This paper reports the synthesis and structure of one of them, 2-cyclohexyl-6-(2-oxo-2H-chromen-3-yl)imidazo[2,1-b][1,3,4]thiadiazole-5-carbaldehyde. The compound crystallizes in the monoclinic space group P21/c with a=17.316(3)Å, b=6.5420(9)Å, c =17.056(3)Å, β=112.909(2)°, V=1779.7(4)Å3, z=4. The, Imidazo[2,1-b][1,3,4] thiadiazole and the coumarin ring systems are each planar but inclined at an angle of 48.14(2)° towards each other. The crystal structure is stabilized by C-H O interactions. Springer Science+Business Media, LLC, 2007 Imidazo[2,1-b][1,3,4] thiadiazole derivatives nationallicence Coumarin nationallicence Vilsmeier-Haack reaction nationallicence crystal structure analysis nationallicence Begum Noor Department of Studies in Chemistry, Bangalore University, Central College Campus, 560001, Bangalore, India aut Vasundhara D. Department of Studies in Chemistry, Bangalore University, Central College Campus, 560001, Bangalore, India aut Girija C. Department of Studies in Chemistry, Bangalore University, Central College Campus, 560001, Bangalore, India aut Kolavi G. Department of Chemistry, Karnatak University, 580003, Dharwad, India aut Hegde V. Department of Chemistry, Karnatak University, 580003, Dharwad, India aut Khazi I. Department of Chemistry, Karnatak University, 580003, Dharwad, India aut Journal of Chemical Crystallography Kluwer Academic Publishers-Plenum Publishers; http://www.springer-ny.com 37/3(2007-03-01), 193-198 1074-1542 37:3<193 2007 37 10870 https://doi.org/10.1007/s10870-006-9159-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10870-006-9159-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Begum Noor Department of Studies in Chemistry, Bangalore University, Central College Campus, 560001, Bangalore, India aut NATIONALLICENCE 700 1- Vasundhara D. Department of Studies in Chemistry, Bangalore University, Central College Campus, 560001, Bangalore, India aut NATIONALLICENCE 700 1- Girija C. Department of Studies in Chemistry, Bangalore University, Central College Campus, 560001, Bangalore, India aut NATIONALLICENCE 700 1- Kolavi G. Department of Chemistry, Karnatak University, 580003, Dharwad, India aut NATIONALLICENCE 700 1- Hegde V. Department of Chemistry, Karnatak University, 580003, Dharwad, India aut NATIONALLICENCE 700 1- Khazi I. Department of Chemistry, Karnatak University, 580003, Dharwad, India aut NATIONALLICENCE 773 0- Journal of Chemical Crystallography Kluwer Academic Publishers-Plenum Publishers; http://www.springer-ny.com 37/3(2007-03-01), 193-198 1074-1542 37:3<193 2007 37 10870 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer