caa a22 4500 463185366 CHVBK 20180406164851.0 cr unu---uuuuu 170326e20070101xx s 000 0 eng 10.1007/s00726-006-0262-9 doi (NATIONALLICENCE)springer-10.1007/s00726-006-0262-9 High concentrations of D-amino acids in human gastric juice [Elektronische Daten] [Y. Nagata, T. Sato, N. Enomoto, Y. Ishii, K. Sasaki, T. Yamada] Summary.: The concentrations of free D- and L-amino acids were determined in the gastric juice from four groups: patients suffering from early gastric carcinoma with or without Helicobacter pylori infection, and patients without carcinoma but with peptic ulcers, duodenal ulcers or chronic gastritis with or without H. pylori infection. H. pylori is a bacterium associated with gastric inflammation and peptic ulcers and is a risk factor for stomach cancer. The highest D-amino acid ratios (free D-amino acid concentration to the total corresponding free D- and L-amino acid concentration) were 29%, 26%, 18%, 4% and 1% for proline, alanine, serine, aspartate and glutamate, respectively. The gastric juice levels of L-alanine, L-serine, L-proline, L-glutamate and D-alanine in the samples obtained from subjects bearing early gastric carcinoma and H. pylori were significantly higher than in the samples from the other three groups. Except for D-alanine, there was no correlation between the D-amino acid concentrations and presence of carcinoma or H. pylori. Springer-Verlag, 2006 Keywords: D-Amino acids - Gastric juice - Gastric carcinoma - H. pylori nationallicence Nagata Y. Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, Tokyo, Japan aut Sato T. First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan aut Enomoto N. First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan aut Ishii Y. Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, Tokyo, Japan aut Sasaki K. Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, Tokyo, Japan aut Yamada T. Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, Tokyo, Japan aut Amino Acids Springer-Verlag 32/1(2007-01-01), 137-140 0939-4451 32:1<137 2007 32 726 https://doi.org/10.1007/s00726-006-0262-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00726-006-0262-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nagata Y. Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, Tokyo, Japan aut NATIONALLICENCE 700 1- Sato T. First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan aut NATIONALLICENCE 700 1- Enomoto N. First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan aut NATIONALLICENCE 700 1- Ishii Y. Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, Tokyo, Japan aut NATIONALLICENCE 700 1- Sasaki K. Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, Tokyo, Japan aut NATIONALLICENCE 700 1- Yamada T. Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, Tokyo, Japan aut NATIONALLICENCE 773 0- Amino Acids Springer-Verlag 32/1(2007-01-01), 137-140 0939-4451 32:1<137 2007 32 726 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer