caa a22 4500 463188721 CHVBK 20180406164901.0 cr unu---uuuuu 170326e20070501xx s 000 0 eng 10.1007/s10973-006-8005-4 doi (NATIONALLICENCE)springer-10.1007/s10973-006-8005-4 Technologicalquality determination of pharmaceutical disintegrant by DSC cooling and DSCphotovisual [Elektronische Daten] [Ana Medeiros, Lidiane Correia, Mônica Simões, R. Macêdo] A number of disintegrants are available on the market. They improve tablets' disintegration. The objective of this work is the comparison of the technological quality parameters of disintegrants using different analytical techniques. Three batches of disintegrants and their binary mixtures (water:disintegrants) were investigated. Cooling experiments were used from -30 up to 200°C. The data obtained showed calorimetric differences between the samples. In the binary mixtures water showed different crystallization behaviour from the one found in the literature. According to the results DSC technique helped the quality control of different disintegrants. Springer-Verlag, 2007 crystallization water nationallicence disintegrants nationallicence DSC cooling nationallicence DSC photovisual and particles size nationallicence Medeiros Ana Unified Laboratory of Medicine Development and Assay (LUDEM), Pharmacy Department, Federal University of Paraíba, Campus I, 58059-900, João Pessoa, Paraíba, Brazil aut Correia Lidiane Unified Laboratory of Medicine Development and Assay (LUDEM), Pharmacy Department, Federal University of Paraíba, Campus I, 58059-900, João Pessoa, Paraíba, Brazil aut Simões Mônica Pharmacy Department, Stadual University of Paraíba, Campina Grande, Paraíba, Brazil aut Macêdo R. Unified Laboratory of Medicine Development and Assay (LUDEM), Pharmacy Department, Federal University of Paraíba, Campus I, 58059-900, João Pessoa, Paraíba, Brazil aut Journal of Thermal Analysis and Calorimetry Kluwer Academic Publishers 88/2(2007-05-01), 311-315 1388-6150 88:2<311 2007 88 10973 https://doi.org/10.1007/s10973-006-8005-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10973-006-8005-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Medeiros Ana Unified Laboratory of Medicine Development and Assay (LUDEM), Pharmacy Department, Federal University of Paraíba, Campus I, 58059-900, João Pessoa, Paraíba, Brazil aut NATIONALLICENCE 700 1- Correia Lidiane Unified Laboratory of Medicine Development and Assay (LUDEM), Pharmacy Department, Federal University of Paraíba, Campus I, 58059-900, João Pessoa, Paraíba, Brazil aut NATIONALLICENCE 700 1- Simões Mônica Pharmacy Department, Stadual University of Paraíba, Campina Grande, Paraíba, Brazil aut NATIONALLICENCE 700 1- Macêdo R. Unified Laboratory of Medicine Development and Assay (LUDEM), Pharmacy Department, Federal University of Paraíba, Campus I, 58059-900, João Pessoa, Paraíba, Brazil aut NATIONALLICENCE 773 0- Journal of Thermal Analysis and Calorimetry Kluwer Academic Publishers 88/2(2007-05-01), 311-315 1388-6150 88:2<311 2007 88 10973 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer