caa a22 4500 463188810 CHVBK 20180406164901.0 cr unu---uuuuu 170326e20070501xx s 000 0 eng 10.1007/s10973-006-8128-7 doi (NATIONALLICENCE)springer-10.1007/s10973-006-8128-7 Thermalstability study of the protease inhibitors [Elektronische Daten] Nelfinavir mesylate and atazanavir sulfate [Katarzyna Michalik, Zofia Drzazga, Anna Michnik, M. Kaszuba] A thermal and kinetic analysis of two protease inhibitors: nelfinavir mesylate and atazanavir sulfate, were carried out to find their thermal stability. DSC curves of both drugs showed exothermic transition. This observed process resulted in two steps. Obtained apparent activation energy pointed at low stability of studied protease inhibitors in water solutions. Springer-Verlag, 2007 atazanavir sulfate nationallicence DSC nationallicence nelfinavir mesylate nationallicence thermal analysis nationallicence Michalik Katarzyna A. Chełkowski' Institute of Physics, Department of Medical Physics, University of Silesia, ul. Uniwersytecka 4, 40-007, Katowice, Poland aut Drzazga Zofia A. Chełkowski' Institute of Physics, Department of Medical Physics, University of Silesia, ul. Uniwersytecka 4, 40-007, Katowice, Poland aut Michnik Anna A. Chełkowski' Institute of Physics, Department of Medical Physics, University of Silesia, ul. Uniwersytecka 4, 40-007, Katowice, Poland aut Kaszuba M. Department of Conservative and Peropdontology, Medical University of Silesia, Pl. Akademicki 17, 41-902, Bytom, Poland aut Journal of Thermal Analysis and Calorimetry Kluwer Academic Publishers 88/2(2007-05-01), 401-404 1388-6150 88:2<401 2007 88 10973 https://doi.org/10.1007/s10973-006-8128-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10973-006-8128-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Michalik Katarzyna A. Chełkowski' Institute of Physics, Department of Medical Physics, University of Silesia, ul. Uniwersytecka 4, 40-007, Katowice, Poland aut NATIONALLICENCE 700 1- Drzazga Zofia A. Chełkowski' Institute of Physics, Department of Medical Physics, University of Silesia, ul. Uniwersytecka 4, 40-007, Katowice, Poland aut NATIONALLICENCE 700 1- Michnik Anna A. Chełkowski' Institute of Physics, Department of Medical Physics, University of Silesia, ul. Uniwersytecka 4, 40-007, Katowice, Poland aut NATIONALLICENCE 700 1- Kaszuba M. Department of Conservative and Peropdontology, Medical University of Silesia, Pl. Akademicki 17, 41-902, Bytom, Poland aut NATIONALLICENCE 773 0- Journal of Thermal Analysis and Calorimetry Kluwer Academic Publishers 88/2(2007-05-01), 401-404 1388-6150 88:2<401 2007 88 10973 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer