caa a22 4500 463191226 CHVBK 20180406164909.0 cr unu---uuuuu 170326e20070901xx s 000 0 eng 10.1007/s10973-006-7902-x doi (NATIONALLICENCE)springer-10.1007/s10973-006-7902-x Microcalorimetric investigation of the growth of the Escherichia coli DH5α in different antibiotics [Elektronische Daten] [L. Yang, S. Qiu, F. Xu, L. Sun, Z. Zhao, J. Liang, C. Song] The effects of Amoxicillin Sodium and Cefuroxime Sodium on the growth of E. coli DH5α were investigated by microcalorimetry. The metabolic power-time curves of E. coli DH5α growth were determined by using a TAM air isothermal microcalorimeter at 37°C. By evaluation of the obtained parameters, such as growth rate constants (k), inhibitory ratio (I), the maximum heat power (P m) and the time of the maximum heat power (t m), one found that the inhibitory activity of Amoxicillin Sodium vs. E. coli DH5α is enhanced with the increasing of the Amoxicillin Sodium concentration, and the Cefuroxime Sodium has a stimulatory effect on the E. coli DH5α growth when the concentration is about 1 μg mL−1. The IC50 for the Amoxicillin Sodium and the Cefuroxime Sodium are 1.6 and 2.0 μg mL−1, respectively, it implicates that the E. coli DH5α is more sensitive to Amoxicillin Sodium than Cefuroxime Sodium. Springer Science+Business Media LLC, 2007 Amoxicillin Sodium nationallicence Cefuroxime Sodium nationallicence E. coli DH5α nationallicence inhibition nationallicence microcalorimetry nationallicence Yang L. Materials and Thermochemistry Laboratory, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, 116023, Dalian, P.R. China aut Qiu S. Materials and Thermochemistry Laboratory, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, 116023, Dalian, P.R. China aut Xu F. Materials and Thermochemistry Laboratory, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, 116023, Dalian, P.R. China aut Sun L. Materials and Thermochemistry Laboratory, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, 116023, Dalian, P.R. China aut Zhao Z. Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, 116023, Dalian, P.R. China aut Liang J. Hunan Institute of Drug Detection, 410001, Changsha, P.R. China aut Song C. Dalian Institute of Drug Detection, 116021, Dalian, P.R. China aut Journal of Thermal Analysis and Calorimetry Springer US; http://www.springer-ny.com 89/3(2007-09-01), 875-879 1388-6150 89:3<875 2007 89 10973 https://doi.org/10.1007/s10973-006-7902-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10973-006-7902-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yang L. Materials and Thermochemistry Laboratory, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, 116023, Dalian, P.R. China aut NATIONALLICENCE 700 1- Qiu S. Materials and Thermochemistry Laboratory, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, 116023, Dalian, P.R. China aut NATIONALLICENCE 700 1- Xu F. Materials and Thermochemistry Laboratory, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, 116023, Dalian, P.R. China aut NATIONALLICENCE 700 1- Sun L. Materials and Thermochemistry Laboratory, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, 116023, Dalian, P.R. China aut NATIONALLICENCE 700 1- Zhao Z. Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, 116023, Dalian, P.R. China aut NATIONALLICENCE 700 1- Liang J. Hunan Institute of Drug Detection, 410001, Changsha, P.R. China aut NATIONALLICENCE 700 1- Song C. Dalian Institute of Drug Detection, 116021, Dalian, P.R. China aut NATIONALLICENCE 773 0- Journal of Thermal Analysis and Calorimetry Springer US; http://www.springer-ny.com 89/3(2007-09-01), 875-879 1388-6150 89:3<875 2007 89 10973 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer