caa a22 4500 463191390 CHVBK 20180406164910.0 cr unu---uuuuu 170326e20070901xx s 000 0 eng 10.1007/s10973-006-7899-1 doi (NATIONALLICENCE)springer-10.1007/s10973-006-7899-1 Studyon biological effect of a kind of hetero-bimetallic Schiff-base on Escherichia coli [Elektronische Daten] [L. Peng, L. Yi, L. Xi, R. Lifang, Z. Chaocan] The biological activity of a kind of hetero-bimetallic Schiff-base complex was studied using Escherichia coli (E. coli) cell as the target. By microcalorimetry, the difference of anti-bacterial activity between the binuclear Schiff-base and the ligand was determined and analyzed. To analyze the inhibition of the bacterial growth internally, the E. coli cells grown in the presence of hetero-bimetallic Schiff-base complex were observed by scanning electron microscopy. The images in high resolution revealed the damage of outer cell membrane caused the inhibitory effect on E. coli. Inductively coupled plasma-mass spectrometry results proved the absorption of the complex by cells, which confirmed the interaction between the Schiff-base and biological macromolecule. Springer Science+Business Media LLC, 2007 anti-bacterial nationallicence coordination nationallicence inhibition nationallicence microcalorimetry nationallicence Schiff-base nationallicence Peng L. School of Sciences, Wuhan University of Technology, 430070, Wuhan, China aut Yi L. College of Chemistry and Molecular Science, Wuhan University, 430072, Wuhan, China aut Xi L. School of Sciences, Wuhan University of Technology, 430070, Wuhan, China aut Lifang R. State key laboratory of agricultural microbiology, Huazhong Agricultural University, 430070, Wuhan, China aut Chaocan Z. School of Material Science and Technology, Wuhan University of Technology, 430070, Wuhan, China aut Journal of Thermal Analysis and Calorimetry Springer US; http://www.springer-ny.com 89/3(2007-09-01), 881-885 1388-6150 89:3<881 2007 89 10973 https://doi.org/10.1007/s10973-006-7899-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10973-006-7899-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Peng L. School of Sciences, Wuhan University of Technology, 430070, Wuhan, China aut NATIONALLICENCE 700 1- Yi L. College of Chemistry and Molecular Science, Wuhan University, 430072, Wuhan, China aut NATIONALLICENCE 700 1- Xi L. School of Sciences, Wuhan University of Technology, 430070, Wuhan, China aut NATIONALLICENCE 700 1- Lifang R. State key laboratory of agricultural microbiology, Huazhong Agricultural University, 430070, Wuhan, China aut NATIONALLICENCE 700 1- Chaocan Z. School of Material Science and Technology, Wuhan University of Technology, 430070, Wuhan, China aut NATIONALLICENCE 773 0- Journal of Thermal Analysis and Calorimetry Springer US; http://www.springer-ny.com 89/3(2007-09-01), 881-885 1388-6150 89:3<881 2007 89 10973 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer