caa a22 4500 463193776 CHVBK 20180406164916.0 cr unu---uuuuu 170326e20071001xx s 000 0 eng 10.1007/s00420-007-0188-x doi (NATIONALLICENCE)springer-10.1007/s00420-007-0188-x Inhalation and dietary exposure to polycyclic aromatic hydrocarbons and urinary 1-hydroxypyrene in non-smoking university students [Elektronische Daten] [Kaori Suzuki, Jun Yoshinaga] Objective: To examine which exposure pathway, dietary or inhalation, contribute more to the exposure to, and/or internal dose of, polycyclic aromatic hydrocarbons (PAHs) of non-smoking Japanese. Methods: Duplicated diet, personal air samples and 24-h urine were collected from14 non-smoking male university students without occupational exposure and the concentrations of PAHs in diet and air and that of 1-hydroxypyrene (1-OHP) in urine were measured with HPLC-fluorescence detector. Results: Daily dietary exposure contributed more than 90% of the total (diet+inhalation) daily exposure level for pyrene (diet/inhalation: 757/1.2ng/day), benzo[k]fluoranthene (25/1.7ng/day) and benzo[a]pyrene (91/2.1ng/day). Urinary excretion of 1-OHP (median: 37ng/day) was statistically significantly correlated only with dietary PAHs exposure level but not with inhalation. Conclusion: Countermeasures to lower PAHs levels in atmosphere has been successful in Japan and more attention should be directed to dietary exposure to PAHs for reducing cancer risk in general population. Springer-Verlag, 2007 Polycyclic aromatic hydrocarbons nationallicence Exposure nationallicence Diet nationallicence Inhalation nationallicence Urinary 1-hydroxypyrene nationallicence Suzuki Kaori Department of Environmental Studies, The University of Tokyo, Kashiwanoha 5-1-5, Kashiwa, 277-8563, Chiba, Japan aut Yoshinaga Jun Department of Environmental Studies, The University of Tokyo, Kashiwanoha 5-1-5, Kashiwa, 277-8563, Chiba, Japan aut International Archives of Occupational and Environmental Health Springer-Verlag 81/1(2007-10-01), 115-121 0340-0131 81:1<115 2007 81 420 https://doi.org/10.1007/s00420-007-0188-x text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00420-007-0188-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Suzuki Kaori Department of Environmental Studies, The University of Tokyo, Kashiwanoha 5-1-5, Kashiwa, 277-8563, Chiba, Japan aut NATIONALLICENCE 700 1- Yoshinaga Jun Department of Environmental Studies, The University of Tokyo, Kashiwanoha 5-1-5, Kashiwa, 277-8563, Chiba, Japan aut NATIONALLICENCE 773 0- International Archives of Occupational and Environmental Health Springer-Verlag 81/1(2007-10-01), 115-121 0340-0131 81:1<115 2007 81 420 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer