caa a22 4500 463193857 CHVBK 20180406164916.0 cr unu---uuuuu 170326e20071101xx s 000 0 eng 10.1007/s00420-007-0207-y doi (NATIONALLICENCE)springer-10.1007/s00420-007-0207-y German cattle allergy study (CAS): public health relevance of cattle-allergic farmers [Elektronische Daten] [Astrid Heutelbeck, Nico Janicke, Reinhard Hilgers, Birgitta Kütting, Hans Drexler, Ernst Hallier, Heike Bickeböller] Introduction: Allergic reactions caused by animals are a common and significant occupational health concern. In a large population-based study on occupational asthma in Europe, farming has been among the occupations with the highest risk. Objectives: Characteristics of cattle-allergic farmers are described in a retrospective observational design. Methods: The study covers farmers from all regions of Germany which were reported to the Agricultural Institutions for Statutory Accident Insurance and Prevention (Landwirtschaftliche Berufsgenossenschaften, LBGs) between 1990 (January) and 2002 (December) with a suspected occupational cattle-allergic airways disease. For these farmers, the following parameters were considered: age, gender, onset of airways symptoms related to contact with cattle, begin of employment disability, total and specific Immunoglobulin E (IgE) against cattle allergens, and results of lung function measurements. Results: A total of 513 patients (age 14-74, mean 40.7years; 45.6% women, 54.4% men) had been reported for a suspected occupational cattle-allergic airways disease. Of these patients 24.8% showed cattle-related symptoms of asthma, 11.7% of rhinitis, and 60% of both asthma and rhinitis, while only 34.5% of all reported patients showed an airways obstruction in the first documented lung function test. A total of 62.5% out of the group of patients with an officially recognized occupational disease (42.1%, n=216) have an initial employment disability with a rating of 20% or above. Conclusions: Our results underline the high public health relevance of cattle allergy in farmers, especially in the light of the large number of young patients. Considering the known difficulties in diagnosing cattle allergy due to the number of false negative test results, we are convinced that its relevance is even higher than the number of reported cases suggests. The high rate of initial employment disability among the affected patients underlines the need for improved preventive measures. Springer-Verlag, 2007 Cattle allergy nationallicence Occupational disease nationallicence Employment disability nationallicence Prevention nationallicence Heutelbeck Astrid Abteilung Arbeits- und Sozialmedizin, Georg-August-Universität, Waldweg 37, 37073, Göttingen, Germany aut Janicke Nico Institut für Mathematische Stochastik, Abteilung Genetische Epidemiologie, Georg-August-Universität, Humboldtallee 32, 37073, Göttingen, Germany aut Hilgers Reinhard Abteilung Medizinische Statistik, Georg-August-Universität, Humboldtallee 32, 37073, Göttingen, Germany aut Kütting Birgitta Institut für Arbeits-, Sozial- und Umweltmedizin, Friedrich Alexander Universität Erlangen-Nürnberg, Schillerstr. 25+29, 91054, Erlangen, Germany aut Drexler Hans Institut für Arbeits-, Sozial- und Umweltmedizin, Friedrich Alexander Universität Erlangen-Nürnberg, Schillerstr. 25+29, 91054, Erlangen, Germany aut Hallier Ernst Abteilung Arbeits- und Sozialmedizin, Georg-August-Universität, Waldweg 37, 37073, Göttingen, Germany aut Bickeböller Heike Abteilung Genetische Epidemiologie, Georg-August-Universität, Humboldtallee 32, 37073, Göttingen, Germany aut International Archives of Occupational and Environmental Health Springer-Verlag 81/2(2007-11-01), 201-208 0340-0131 81:2<201 2007 81 420 https://doi.org/10.1007/s00420-007-0207-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00420-007-0207-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Heutelbeck Astrid Abteilung Arbeits- und Sozialmedizin, Georg-August-Universität, Waldweg 37, 37073, Göttingen, Germany aut NATIONALLICENCE 700 1- Janicke Nico Institut für Mathematische Stochastik, Abteilung Genetische Epidemiologie, Georg-August-Universität, Humboldtallee 32, 37073, Göttingen, Germany aut NATIONALLICENCE 700 1- Hilgers Reinhard Abteilung Medizinische Statistik, Georg-August-Universität, Humboldtallee 32, 37073, Göttingen, Germany aut NATIONALLICENCE 700 1- Kütting Birgitta Institut für Arbeits-, Sozial- und Umweltmedizin, Friedrich Alexander Universität Erlangen-Nürnberg, Schillerstr. 25+29, 91054, Erlangen, Germany aut NATIONALLICENCE 700 1- Drexler Hans Institut für Arbeits-, Sozial- und Umweltmedizin, Friedrich Alexander Universität Erlangen-Nürnberg, Schillerstr. 25+29, 91054, Erlangen, Germany aut NATIONALLICENCE 700 1- Hallier Ernst Abteilung Arbeits- und Sozialmedizin, Georg-August-Universität, Waldweg 37, 37073, Göttingen, Germany aut NATIONALLICENCE 700 1- Bickeböller Heike Abteilung Genetische Epidemiologie, Georg-August-Universität, Humboldtallee 32, 37073, Göttingen, Germany aut NATIONALLICENCE 773 0- International Archives of Occupational and Environmental Health Springer-Verlag 81/2(2007-11-01), 201-208 0340-0131 81:2<201 2007 81 420 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer