caa a22 4500 463194535 CHVBK 20180406164919.0 cr unu---uuuuu 170326e20070401xx s 000 0 eng 10.1007/s00420-006-0151-2 doi (NATIONALLICENCE)springer-10.1007/s00420-006-0151-2 Allergy in bakers' apprentices and factors associated to non-participation in a cohort study of allergic sensitization [Elektronische Daten] [Tina Skjold, Sven Nielsen, Katja Adolf, Hans Hoffmann, Ronald Dahl, Torben Sigsgaard] Objective: To describe the prevalence of atopy and respiratory symptoms among baker apprentices at the start of the education and factors associated with non-participation in the study. Methods: A total of 346 students, 22.1(0.6)years of age, mean (SD), from the food production programme of technical colleges in Denmark were invited to participate in a 3year study. Of the students, 187 agreed to participate and filled in a physician-administered questionnaire. The presence of atopy was determined by skin prick test (SPT) and serum allergen specific IgE (SpIgE). Bronchial hyper responsiveness to methacholine (PD20≤1,440μg) was determined. Results: Prevalence of atopy was 32%. The prevalence of symptoms from the lungs and nose was 19.8 and 25.5%, respectively. Significantly, more SPT reactions were seen in males compared to females (39 vs. 22%, P<0.05). Sensitization towards flour was significantly more frequent if determined as SpIgE (7.3%) compared to SPT (0.5%). We found a positive association between atopy and lung symptoms OR 6.1 (2.8-13.2SD) and nasal symptoms OR 3.7 (1.8-7.5SD). The major reason for non-participation was fear of blood sampling (25.5%). Conclusion: The prevalence of atopy in bakers' apprentices was of the same magnitude in the general Danish population. Significantly, more male bakers' apprentices had atopy. This finding has major impact on the diagnostic procedures of occupational allergy in bakery workers emphasizing the need for standardization of the clinical tests. The main reasons for non-participation were, fear of blood-sampling (57%) and the 3years commitment to the follow-up study (39%). Springer-Verlag, 2006 Atopy nationallicence Baker apprentices nationallicence Asthma nationallicence Rhinitis nationallicence Prevalence nationallicence SPT nationallicence Specific IgE nationallicence Sensitization nationallicence Skjold Tina Department of Respiratory Medicine, Aarhus University Hospital, Noerrebrogade 44, 8000, Aarhus C, Denmark aut Nielsen Sven Department of Respiratory Medicine, Aarhus University Hospital, Noerrebrogade 44, 8000, Aarhus C, Denmark aut Adolf Katja Department of Clinical Immunology, Aarhus University Hospital, Noerrebrogade 44, 8000, Aarhus C, Denmark aut Hoffmann Hans Department of Respiratory Medicine, Aarhus University Hospital, Noerrebrogade 44, 8000, Aarhus C, Denmark aut Dahl Ronald Department of Respiratory Medicine, Aarhus University Hospital, Noerrebrogade 44, 8000, Aarhus C, Denmark aut Sigsgaard Torben Department of Environmental and Occupational Medicine, Aarhus University, Aarhus, Denmark aut International Archives of Occupational and Environmental Health Springer-Verlag 80/5(2007-04-01), 458-464 0340-0131 80:5<458 2007 80 420 https://doi.org/10.1007/s00420-006-0151-2 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00420-006-0151-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Skjold Tina Department of Respiratory Medicine, Aarhus University Hospital, Noerrebrogade 44, 8000, Aarhus C, Denmark aut NATIONALLICENCE 700 1- Nielsen Sven Department of Respiratory Medicine, Aarhus University Hospital, Noerrebrogade 44, 8000, Aarhus C, Denmark aut NATIONALLICENCE 700 1- Adolf Katja Department of Clinical Immunology, Aarhus University Hospital, Noerrebrogade 44, 8000, Aarhus C, Denmark aut NATIONALLICENCE 700 1- Hoffmann Hans Department of Respiratory Medicine, Aarhus University Hospital, Noerrebrogade 44, 8000, Aarhus C, Denmark aut NATIONALLICENCE 700 1- Dahl Ronald Department of Respiratory Medicine, Aarhus University Hospital, Noerrebrogade 44, 8000, Aarhus C, Denmark aut NATIONALLICENCE 700 1- Sigsgaard Torben Department of Environmental and Occupational Medicine, Aarhus University, Aarhus, Denmark aut NATIONALLICENCE 773 0- International Archives of Occupational and Environmental Health Springer-Verlag 80/5(2007-04-01), 458-464 0340-0131 80:5<458 2007 80 420 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer