caa a22 4500 463195078 CHVBK 20180406164920.0 cr unu---uuuuu 170326e20071201xx s 000 0 eng 10.1007/s10669-007-9117-5 doi (NATIONALLICENCE)springer-10.1007/s10669-007-9117-5 Influence of static magnetic fields on nerve regeneration invitro [Elektronische Daten] [Betty Sisken, Paul Midkiff, Andrew Tweheus, Marko Markov] Our research involves determining how non-invasive electric and magnetic fields influence neuronal growth invitro. In previous studies we have shown that pulsed electromagnetic fields (PEMF) as well as direct current (DC) alone stimulate neurite outgrowth from dorsal root ganglion explants [Sisken etal. 1984; Sisken etal. (Restor Neurol Neurosci 1:303-309, 1990); Greenebaum etal. (Bioelectromagnetics 17:293-302, 1996)]. A maximum response was obtained when nerve growth factor (NGF) was also present in the medium. The results of our experiments using static magnetic fields of different strengths are presented below and indicate that fields of high magnetic strength (450-900gauss) with added NGF stimulate neurite outgrowth comparable to the response obtained with PEMF plus NGF. Springer Science+Business Media, LLC, 2007 Neurite outgrowth nationallicence Nerve growth factor nationallicence Growth quantitation nationallicence Sisken Betty Center for Biomedical Engineering and Department of Anatomy and Neurobiology, University of Kentucky, 40506-0070, Lexington, KY, USA aut Midkiff Paul Center for Biomedical Engineering and Department of Anatomy and Neurobiology, University of Kentucky, 40506-0070, Lexington, KY, USA aut Tweheus Andrew Center for Biomedical Engineering and Department of Anatomy and Neurobiology, University of Kentucky, 40506-0070, Lexington, KY, USA aut Markov Marko Research International, 14221, Williamsville, NY, USA aut The Environmentalist Springer US; http://www.springer-ny.com 27/4(2007-12-01), 477-481 0251-1088 27:4<477 2007 27 10669 https://doi.org/10.1007/s10669-007-9117-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10669-007-9117-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sisken Betty Center for Biomedical Engineering and Department of Anatomy and Neurobiology, University of Kentucky, 40506-0070, Lexington, KY, USA aut NATIONALLICENCE 700 1- Midkiff Paul Center for Biomedical Engineering and Department of Anatomy and Neurobiology, University of Kentucky, 40506-0070, Lexington, KY, USA aut NATIONALLICENCE 700 1- Tweheus Andrew Center for Biomedical Engineering and Department of Anatomy and Neurobiology, University of Kentucky, 40506-0070, Lexington, KY, USA aut NATIONALLICENCE 700 1- Markov Marko Research International, 14221, Williamsville, NY, USA aut NATIONALLICENCE 773 0- The Environmentalist Springer US; http://www.springer-ny.com 27/4(2007-12-01), 477-481 0251-1088 27:4<477 2007 27 10669 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer