caa a22 4500 463200675 CHVBK 20180405153111.0 cr unu---uuuuu 170326e20071101xx s 000 0 eng 10.1007/s10014-007-0219-z doi (NATIONALLICENCE)springer-10.1007/s10014-007-0219-z The usefulness and problem of intraoperative rapid diagnosis in surgical neuropathology [Elektronische Daten] [Yuji Uematsu, Yoshihiro Owai, Rhuji Okita, Yoshiyuki Tanaka, Toru Itakura] Intraoperative rapid diagnosis has been a useful neurosurgery tool for maximal resection and minimal morbidity. However, only a few studies have been conducted regarding diagnostic accuracy and associated problems. The present study reviews our experience in treating patients and investigates the accuracy and problems associated with intraoperative rapid diagnosis in surgical neuropathology. There were 180 cases of intracranial lesions excluding pituitary lesions. The patients consisted of 89 males and 91 females, ranging from 5 months to 84 years, with a mean age of 46 years. Of the 180 cases, 152 cases received open surgery, 28 cases had stereotactic surgery including a biopsy and were histologically verified. The correlation between the intraoperative diagnosis and the final diagnosis overall was seen in 172 of 180 cases, proving a high diagnostic sensitivity of 95.6%. No correlation was seen in 8 cases (4.4%). The diagnostic inaccuracy was seen in the grading of gliomas and the diagnosis of undifferentiated malignant tumors such as undifferentiated metastatic carcinomas, primitive neuroectodermal tumors (PNETs), and sarcomas. It was also recognized in rare types of histology such as gliomatosis and xanthomatous lesions. These results suggested that the intraoperative rapid diagnosis was quite useful, but that we should also maintain a cautious attitude. The Japan Society of Brain Tumor Pathology, 2007 Diagnostic accuracy nationallicence Frozen section nationallicence Intraoperative rapid diagnosis nationallicence Surgical neuropathology nationallicence Uematsu Yuji School of Health and Nursing Science, Wakayama Medical University, Mikazura 580, 641-0011, Wakayama, Japan aut Owai Yoshihiro Department of Neurological Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan aut Okita Rhuji Department of Neurological Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan aut Tanaka Yoshiyuki Department of Neurological Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan aut Itakura Toru Department of Neurological Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan aut Brain Tumor Pathology Springer-Verlag 24/2(2007-11-01), 47-52 1433-7398 24:2<47 2007 24 10014 https://doi.org/10.1007/s10014-007-0219-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10014-007-0219-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Uematsu Yuji School of Health and Nursing Science, Wakayama Medical University, Mikazura 580, 641-0011, Wakayama, Japan aut NATIONALLICENCE 700 1- Owai Yoshihiro Department of Neurological Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan aut NATIONALLICENCE 700 1- Okita Rhuji Department of Neurological Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan aut NATIONALLICENCE 700 1- Tanaka Yoshiyuki Department of Neurological Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan aut NATIONALLICENCE 700 1- Itakura Toru Department of Neurological Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan aut NATIONALLICENCE 773 0- Brain Tumor Pathology Springer-Verlag 24/2(2007-11-01), 47-52 1433-7398 24:2<47 2007 24 10014 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer