caa a22 4500 463206266 CHVBK 20180405153127.0 cr unu---uuuuu 170326e20071201xx s 000 0 eng 10.1007/s00202-007-0062-6 doi (NATIONALLICENCE)springer-10.1007/s00202-007-0062-6 Information and communication theory in molecular biology [Elektronische Daten] [Pavol Hanus, Bernhard Goebel, Janis Dingel, Johanna Weindl, Juergen Zech, Zaher Dawy, Joachim Hagenauer, Jakob Mueller] The DNA sequencing efforts of the past years together with rapid progress in sequencing technology have generated a huge amount of sequence data available in public molecular databases. This recent development makes it statistically feasible to apply universal concepts from Shannon's information theory to problems in molecular biology, e.g to use mutual information for gene mapping and phylogenetic classification. Additionally, the genetic information in the cell is continuously subject to mutations. However, it has to be passed from generation to generation with high fidelity, raising the question of existence of error protection and correction mechanisms similar to those used in technical communication systems. Finally, better understanding of genetic information processing on the molecular level in the cell can be acquired by looking for parallels to well established models in communication theory, e.g. there exist analogies between gene expression and frame synchronization. Springer-Verlag, 2007 Information theory nationallicence Communication theory nationallicence Molecular genetics nationallicence Classification nationallicence Gene mapping nationallicence Error correction nationallicence Frame synchronization nationallicence Hanus Pavol Institute for Communications Engineering, TU-München, Arcisstr. 21, 80290, Munich, Germany aut Goebel Bernhard Institute for Communications Engineering, TU-München, Arcisstr. 21, 80290, Munich, Germany aut Dingel Janis Institute for Communications Engineering, TU-München, Arcisstr. 21, 80290, Munich, Germany aut Weindl Johanna Institute for Communications Engineering, TU-München, Arcisstr. 21, 80290, Munich, Germany aut Zech Juergen Institute for Statistical Medicine and Epidemiology, TU-München, Clinic "Rechts der Isar”, Ismaninger Str. 22, 81675, Munich, Germany aut Dawy Zaher Department of Electrical and Computer Engineering, American University of Beirut, Riad El-Solh, P.O. Box 11-0236, 1107 2020, Beirut, Lebanon aut Hagenauer Joachim Institute for Communications Engineering, TU-München, Arcisstr. 21, 80290, Munich, Germany aut Mueller Jakob Max Planck Institute for Ornithology, Postfach 1564, Haus Nr. 5, 82319, Seewiesen, Germany aut Electrical Engineering Springer-Verlag 90/2(2007-12-01), 161-173 0948-7921 90:2<161 2007 90 202 https://doi.org/10.1007/s00202-007-0062-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00202-007-0062-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hanus Pavol Institute for Communications Engineering, TU-München, Arcisstr. 21, 80290, Munich, Germany aut NATIONALLICENCE 700 1- Goebel Bernhard Institute for Communications Engineering, TU-München, Arcisstr. 21, 80290, Munich, Germany aut NATIONALLICENCE 700 1- Dingel Janis Institute for Communications Engineering, TU-München, Arcisstr. 21, 80290, Munich, Germany aut NATIONALLICENCE 700 1- Weindl Johanna Institute for Communications Engineering, TU-München, Arcisstr. 21, 80290, Munich, Germany aut NATIONALLICENCE 700 1- Zech Juergen Institute for Statistical Medicine and Epidemiology, TU-München, Clinic "Rechts der Isar”, Ismaninger Str. 22, 81675, Munich, Germany aut NATIONALLICENCE 700 1- Dawy Zaher Department of Electrical and Computer Engineering, American University of Beirut, Riad El-Solh, P.O. Box 11-0236, 1107 2020, Beirut, Lebanon aut NATIONALLICENCE 700 1- Hagenauer Joachim Institute for Communications Engineering, TU-München, Arcisstr. 21, 80290, Munich, Germany aut NATIONALLICENCE 700 1- Mueller Jakob Max Planck Institute for Ornithology, Postfach 1564, Haus Nr. 5, 82319, Seewiesen, Germany aut NATIONALLICENCE 773 0- Electrical Engineering Springer-Verlag 90/2(2007-12-01), 161-173 0948-7921 90:2<161 2007 90 202 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer