caa a22 4500 46321014X CHVBK 20180405153138.0 cr unu---uuuuu 170326e20070401xx s 000 0 eng 10.1007/s00238-007-0116-z doi (NATIONALLICENCE)springer-10.1007/s00238-007-0116-z Prevention of wound dehiscence in palatal surgery by preoperative identification of group A Streptococcus and Staphylococcus aureus [Elektronische Daten] [P. Hupkens, G. Lauret, I. Dubelaar, E. Hartman, P. Spauwen] The goal of this study was to assess the effectiveness of the selective use of prophylactic antibiotics after preoperative microbiological analysis of the oral and nasal cavity. In a retrospective study of wound infections after palatal surgery, 124 patients were included (134 procedures) who underwent all types of corrections of the palate. Standardized cultures from nasal and oropharyngeal mucosa were routinely obtained from all patients admitted for palatal surgery in the week prior to operation. According to existing protocol, every patient revealing group A Streptococcus from the nose or the throat received intravenous amoxicillin-clavulanate perioperatively. The postoperative finding of the combination of partial or complete wound dehiscence, pus, and fever was considered evidence of infection. Cultures from dehisced wounds were subsequently analyzed. Out of 134 procedures performed with this selective use of antibiotics, an infection rate of 6.0% (eight procedures) was noted. None of the patients receiving the amoxicillin-clavulanate prophylaxis showed infection. Patients showing infection revealed preoperative cultures with a diverse flora. Postoperative cultures of these patients showed group A Streptococcus and Staphylococcus aureus as the main pathogens. Despite the retrospective design and limited number of infected patients, cautious conclusions are warranted. When routine cultures from the nasal and oropharyngeal mucosa are obtained preoperatively, infection rate may be reduced by selective use of antibiotics against group A Streptococcus and Staphylococcus aureus. Springer-Verlag, 2007 Palatal surgery nationallicence Wound infection nationallicence Dehiscence nationallicence Prophylactic antibiotics nationallicence Preoperative culture nationallicence Hupkens P. Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Reinier Postlaan 4, 6500 HB, Nijmegen, Netherlands aut Lauret G. Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Reinier Postlaan 4, 6500 HB, Nijmegen, Netherlands aut Dubelaar I. Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Reinier Postlaan 4, 6500 HB, Nijmegen, Netherlands aut Hartman E. Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Reinier Postlaan 4, 6500 HB, Nijmegen, Netherlands aut Spauwen P. Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Reinier Postlaan 4, 6500 HB, Nijmegen, Netherlands aut European Journal of Plastic Surgery Springer-Verlag 29/7(2007-04-01), 321-325 0930-343X 29:7<321 2007 29 238 https://doi.org/10.1007/s00238-007-0116-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00238-007-0116-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hupkens P. Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Reinier Postlaan 4, 6500 HB, Nijmegen, Netherlands aut NATIONALLICENCE 700 1- Lauret G. Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Reinier Postlaan 4, 6500 HB, Nijmegen, Netherlands aut NATIONALLICENCE 700 1- Dubelaar I. Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Reinier Postlaan 4, 6500 HB, Nijmegen, Netherlands aut NATIONALLICENCE 700 1- Hartman E. Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Reinier Postlaan 4, 6500 HB, Nijmegen, Netherlands aut NATIONALLICENCE 700 1- Spauwen P. Department of Plastic and Reconstructive Surgery, Radboud University Medical Center, Reinier Postlaan 4, 6500 HB, Nijmegen, Netherlands aut NATIONALLICENCE 773 0- European Journal of Plastic Surgery Springer-Verlag 29/7(2007-04-01), 321-325 0930-343X 29:7<321 2007 29 238 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer