caa a22 4500 463218698 CHVBK 20180405153205.0 cr unu---uuuuu 170326e20070601xx s 000 0 eng 10.1134/S1061934807060135 doi (NATIONALLICENCE)springer-10.1134/S1061934807060135 Chromatographic separation of paracetamol, caffeine, and aspirin on an adsorbent with immobilized nitrile groups and the analysis of Askofen P tablets [Elektronische Daten] [G. Golubitskii, E. Budko, E. Basova, V. Ivanov, A. Kostarnoi] The chromatographic properties of the pharmaceutical preparations of paracetamol, caffeine, and aspirin are studied on adsorbents with immobilized nitrile groups. The effects of the concentration of acetonitrile and potassium phosphate in the mobile phase and the pH of the mobile phase on the retention of analytes and a possible additive, salicylic acid, are studied. In comparison to a column with a C18 adsorbent used earlier for routine analysis, the chromatograms obtained are characterized by higher separation efficiency, while the proposed separation procedure is more cost-effective and rapid. Pleiades Publishing, Ltd., 2007 Golubitskii G. OAO Pharmstandard-Leksredstva, Vtoraya Agregatnaya ul. 1a/18, 305039, Kursk, Russia aut Budko E. Kursk State Medical University, ul. K. Marksa 3, 305004, Kursk, Russia aut Basova E. Dubna International University of Nature, Society, and Human Being, Universitetskaya ul. 19, 141980, Dubna, Moscow oblast, Russia aut Ivanov V. Department of Chemistry, Moscow State University, 119992, Vorob'evy gory, Moscow, Russia aut Kostarnoi A. OAO Pharmstandard-Leksredstva, Vtoraya Agregatnaya ul. 1a/18, 305039, Kursk, Russia aut Journal of Analytical Chemistry Nauka/Interperiodica 62/6(2007-06-01), 571-574 1061-9348 62:6<571 2007 62 10809 https://doi.org/10.1134/S1061934807060135 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1134/S1061934807060135 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Golubitskii G. OAO Pharmstandard-Leksredstva, Vtoraya Agregatnaya ul. 1a/18, 305039, Kursk, Russia aut NATIONALLICENCE 700 1- Budko E. Kursk State Medical University, ul. K. Marksa 3, 305004, Kursk, Russia aut NATIONALLICENCE 700 1- Basova E. Dubna International University of Nature, Society, and Human Being, Universitetskaya ul. 19, 141980, Dubna, Moscow oblast, Russia aut NATIONALLICENCE 700 1- Ivanov V. Department of Chemistry, Moscow State University, 119992, Vorob'evy gory, Moscow, Russia aut NATIONALLICENCE 700 1- Kostarnoi A. OAO Pharmstandard-Leksredstva, Vtoraya Agregatnaya ul. 1a/18, 305039, Kursk, Russia aut NATIONALLICENCE 773 0- Journal of Analytical Chemistry Nauka/Interperiodica 62/6(2007-06-01), 571-574 1061-9348 62:6<571 2007 62 10809 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer