caa a22 4500 463219139 CHVBK 20180405153206.0 cr unu---uuuuu 170326e20070701xx s 000 0 eng 10.1134/S1061934807070088 doi (NATIONALLICENCE)springer-10.1134/S1061934807070088 Kinetic-chromatographic determination of 4-methylaminoantipyrine in Pentalgin N and Pentalgin FS tablets [Elektronische Daten] [G. Golubitskii, E. Budko, E. Basova, V. Ivanov] 4-Methylaminoantipyrine (4-MAAP) is the main product of analgin decomposition in aqueous-organic solutions used in the analysis of Pentalgin N and Pentalgin FS tablets. The determination of 4-MAAP in tablets is complicated by the fast decomposition of analgin in the course of sample dissolution. The use of nonaqueous solvents in subsequent HPLC analysis is unreasonable, because the shapes of analyte peaks are deteriorated and the decomposition of analgin is not prevented. A procedure for the kinetic-chromatographic determination of both 4-MAAP in tablets and its amount at the moment of sample dissolution is proposed. Pleiades Publishing, Ltd., 2007 Golubitskii G. OAO Farmstandart-Leksredstva, Vtoraya Agregatnaya ul. 1a/18, 305039, Kursk, Russia aut Budko E. Kursk State Medical University, ul. K. Marksa 3, 305004, Kursk, Russia aut Basova E. Dubna International University of Nature, Society, and Human Being, Universitetskaya ul. 19, 141980, Dubna, Moscow oblast, Russia aut Ivanov V. Department of Chemistry, Moscow State University, 119992, Vorob'evy gory, Moscow, Russia aut Journal of Analytical Chemistry Nauka/Interperiodica 62/7(2007-07-01), 658-664 1061-9348 62:7<658 2007 62 10809 https://doi.org/10.1134/S1061934807070088 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1134/S1061934807070088 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Golubitskii G. OAO Farmstandart-Leksredstva, Vtoraya Agregatnaya ul. 1a/18, 305039, Kursk, Russia aut NATIONALLICENCE 700 1- Budko E. Kursk State Medical University, ul. K. Marksa 3, 305004, Kursk, Russia aut NATIONALLICENCE 700 1- Basova E. Dubna International University of Nature, Society, and Human Being, Universitetskaya ul. 19, 141980, Dubna, Moscow oblast, Russia aut NATIONALLICENCE 700 1- Ivanov V. Department of Chemistry, Moscow State University, 119992, Vorob'evy gory, Moscow, Russia aut NATIONALLICENCE 773 0- Journal of Analytical Chemistry Nauka/Interperiodica 62/7(2007-07-01), 658-664 1061-9348 62:7<658 2007 62 10809 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer