caa a22 4500 463219465 CHVBK 20180405153207.0 cr unu---uuuuu 170326e20070301xx s 000 0 eng 10.1134/S1061934807030069 doi (NATIONALLICENCE)springer-10.1134/S1061934807030069 Sequential injection technique for the determination of chlorpromazine hydrochloride in pure form and pharmaceutical formulations [Elektronische Daten] [Suling Feng, Cunhong Li, Jing Fan, Xingguo Chen] A simple, economical, and automated spectrophotometric method for the determination of chlorpromazine hydrochloride by sequential injection analysis using ammonium metavanadate as colorimetric reagent is proposed. The various chemical and physical conditions that affected the reaction have been thoroughly investigated. The calibration curve was linear within the range 10-100 μg/mL. The detection limit (S/N = 3) was 0.7 μg/mL and the limit of quantification (S/N = 10) was 2.3 μg/mL. The sampling frequency was 22 h−1. The method has been used for the determination of chlorpromazine hydrochloride in pure form and pharmaceutical formulations. The t-test has revealed that there is no evidence of significant differences between the obtained results at the 95% confidence level. The method can be applied to the quantitative determination of chlorpromazine hydrochloride. It is also applicable in the quality control of chlorpromazine hydrochloride preparations. Pleiades Publishing, Ltd., 2007 Feng Suling College of Chemistry and Environmental Science, Henan Normal University, 453007, Xinxiang, China aut Li Cunhong Department of Biochemistry and Environmental Engineering, Jiaozuo University, 454000, Jiaozuo, China aut Fan Jing College of Chemistry and Environmental Science, Henan Normal University, 453007, Xinxiang, China aut Chen Xingguo Department of Chemistry, Lanzhou University, 730000, Lanzhou, China aut Journal of Analytical Chemistry Nauka/Interperiodica 62/3(2007-03-01), 233-237 1061-9348 62:3<233 2007 62 10809 https://doi.org/10.1134/S1061934807030069 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1134/S1061934807030069 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Feng Suling College of Chemistry and Environmental Science, Henan Normal University, 453007, Xinxiang, China aut NATIONALLICENCE 700 1- Li Cunhong Department of Biochemistry and Environmental Engineering, Jiaozuo University, 454000, Jiaozuo, China aut NATIONALLICENCE 700 1- Fan Jing College of Chemistry and Environmental Science, Henan Normal University, 453007, Xinxiang, China aut NATIONALLICENCE 700 1- Chen Xingguo Department of Chemistry, Lanzhou University, 730000, Lanzhou, China aut NATIONALLICENCE 773 0- Journal of Analytical Chemistry Nauka/Interperiodica 62/3(2007-03-01), 233-237 1061-9348 62:3<233 2007 62 10809 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer