caa a22 4500 463220595 CHVBK 20180405153210.0 cr unu---uuuuu 170326e20070201xx s 000 0 eng 10.1134/S1061934807020037 doi (NATIONALLICENCE)springer-10.1134/S1061934807020037 Matrix effect on the enantiorecognition ability of adsorbents based on heptakis(6-amino-6-deoxy)-β-cyclodextrin [Elektronische Daten] [E. Potekhina, I. Anan'eva, E. Shapovalova, S. Lopatin, V. Varlamov, O. Shpigun] Four adsorbents were synthesized by immobilizing a chiral selector, heptakis(6-amino-6-deoxy)-β-cyclodextrin, on different silica matrices, such as LiChrosorb Si 100, 10 μm; Silasorb SPH Amin, 5 μm; Kromasil 100-5-Sil, 5 μm; and Kromasil 300-5-Sil, 5 μm. The surface of adsorbents was examined by low-temperature nitrogen adsorption, and the structural properties of substrates and adsorbents were studied by electron microscopy. A matrix effect on the enantiorecognition ability of adsorbents was studied in the reversed-phase and polar-organic modes of high performance liquid chromatography using some amino acid derivatives (N-carbobenzyloxy-and tert-butoxycarbonyl-) and profens as examples. The adsorbent based on Kromasil 100-5-Sil possesses the best chromatographic properties. It was shown that the enantiomeric composition and the concentration of the active component in Ibuprofen can be determined. Pleiades Publishing, Ltd., 2007 Potekhina E. Department of Chemistry, Moscow State University, 119992, Vorob'evy gory, Moscow, Russia aut Anan'eva I. Department of Chemistry, Moscow State University, 119992, Vorob'evy gory, Moscow, Russia aut Shapovalova E. Department of Chemistry, Moscow State University, 119992, Vorob'evy gory, Moscow, Russia aut Lopatin S. Bioinzheneriya Center, Russian Academy of Sciences, pr. 60-letiya Oktyabrya 7, 117312, Moscow, Russia aut Varlamov V. Bioinzheneriya Center, Russian Academy of Sciences, pr. 60-letiya Oktyabrya 7, 117312, Moscow, Russia aut Shpigun O. Department of Chemistry, Moscow State University, 119992, Vorob'evy gory, Moscow, Russia aut Journal of Analytical Chemistry Nauka/Interperiodica 62/2(2007-02-01), 113-121 1061-9348 62:2<113 2007 62 10809 https://doi.org/10.1134/S1061934807020037 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1134/S1061934807020037 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Potekhina E. Department of Chemistry, Moscow State University, 119992, Vorob'evy gory, Moscow, Russia aut NATIONALLICENCE 700 1- Anan'eva I. Department of Chemistry, Moscow State University, 119992, Vorob'evy gory, Moscow, Russia aut NATIONALLICENCE 700 1- Shapovalova E. Department of Chemistry, Moscow State University, 119992, Vorob'evy gory, Moscow, Russia aut NATIONALLICENCE 700 1- Lopatin S. Bioinzheneriya Center, Russian Academy of Sciences, pr. 60-letiya Oktyabrya 7, 117312, Moscow, Russia aut NATIONALLICENCE 700 1- Varlamov V. Bioinzheneriya Center, Russian Academy of Sciences, pr. 60-letiya Oktyabrya 7, 117312, Moscow, Russia aut NATIONALLICENCE 700 1- Shpigun O. Department of Chemistry, Moscow State University, 119992, Vorob'evy gory, Moscow, Russia aut NATIONALLICENCE 773 0- Journal of Analytical Chemistry Nauka/Interperiodica 62/2(2007-02-01), 113-121 1061-9348 62:2<113 2007 62 10809 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer