caa a22 4500 463227182 CHVBK 20180405153230.0 cr unu---uuuuu 170326e20070501xx s 000 0 eng 10.1007/s10853-007-1533-x doi (NATIONALLICENCE)springer-10.1007/s10853-007-1533-x Preparation and characterisation of controlled porosity alginate hydrogels made via a simultaneous micelle templating and internal gelation process [Elektronische Daten] [S. Partap, A. Muthutantri, I. Rehman, G. Davis, J. Darr] Controlled porosity alginate hydrogel monoliths were synthesised by simultaneous micelle templating (MT) and an internal gelation reaction. In water, the self assembling surfactant, cetyltrimethylammonium bromide (CTAB) formed non-spherical micelles that were used as a template for pore formation. The porous microstructure was assessed by mercury intrusion porosimetry (MIP), helium pycnometry, X-ray microtomography (XMT) and scanning electron microscopy (SEM), respectively. The MT hydrogels displayed relatively monodisperse pore size distributions (with pore sizes ranging from 32.5μm to 164.0μm), high total pore volumes (4.5-20.3cm3/g) and high degrees of porosity (83-97%). Some control over pore size distributions was achieved by varying the surfactant concentration; higher surfactant concentrations, led to smaller pores with lower total pore volumes. Uniaxial compression testing revealed that hydrogels made via MT are stable in cell culture media for 28days. Fourier transform infrared (FTIR) spectroscopy data, suggested that all surfactant could be removed from the final product by washing with ethanol and water, making these hydrogels potentially suitable for tissue engineering (TE) applications. Springer Science+Business Media, LLC, 2007 Partap S. Department of Materials, Queen Mary University of London, Mile End, E1 4NS, London, UK aut Muthutantri A. Department of Materials, Queen Mary University of London, Mile End, E1 4NS, London, UK aut Rehman I. IRC in Biomedical Materials, Queen Mary University of London, Mile End, E1 4NS, London, UK aut Davis G. Dental Biophysics Section, Institute of Dentistry, Queen Mary University of London, Mile End Road, E1 4NS, London, UK aut Darr J. Department of Materials, Queen Mary University of London, Mile End, E1 4NS, London, UK aut Journal of Materials Science Springer US; http://www.springer-ny.com 42/10(2007-05-01), 3502-3507 0022-2461 42:10<3502 2007 42 10853 https://doi.org/10.1007/s10853-007-1533-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10853-007-1533-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Partap S. Department of Materials, Queen Mary University of London, Mile End, E1 4NS, London, UK aut NATIONALLICENCE 700 1- Muthutantri A. Department of Materials, Queen Mary University of London, Mile End, E1 4NS, London, UK aut NATIONALLICENCE 700 1- Rehman I. IRC in Biomedical Materials, Queen Mary University of London, Mile End, E1 4NS, London, UK aut NATIONALLICENCE 700 1- Davis G. Dental Biophysics Section, Institute of Dentistry, Queen Mary University of London, Mile End Road, E1 4NS, London, UK aut NATIONALLICENCE 700 1- Darr J. Department of Materials, Queen Mary University of London, Mile End, E1 4NS, London, UK aut NATIONALLICENCE 773 0- Journal of Materials Science Springer US; http://www.springer-ny.com 42/10(2007-05-01), 3502-3507 0022-2461 42:10<3502 2007 42 10853 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer