caa a22 4500 463231384 CHVBK 20180405153243.0 cr unu---uuuuu 170326e20071201xx s 000 0 eng 10.1007/s10853-007-2008-9 doi (NATIONALLICENCE)springer-10.1007/s10853-007-2008-9 The structure and properties of silver-doped phosphate-based glasses [Elektronische Daten] [I. Ahmed, E. Abou Neel, S. Valappil, S. Nazhat, D. Pickup, D. Carta, D. Carroll, R. Newport, M. Smith, J. Knowles] An undoped and two silver-doped (0, 3 and 5mol% Ag) phosphate glass compositions were investigated for their structure and properties. These compositions had in a previous study been investigated for their antimicrobial properties, and were found to be extremely potent at inhibiting the micro-organisms tested. Thermal, X-ray diffraction (XRD), nuclear magnetic resonance (NMR) and X-ray absorption Near Edge Structure (XANES) studies were used to elucidate the structure of the compositions investigated, whilst degradation and ion release studies were conducted to investigate their properties. No significant differences were found between the T g values of the silver containing glasses, while XRD analysis revealed the presence of a NaCa(PO3)3 phase. NMR showed the dominance of Q2 species, and XANES studies revealed the oxidation state of silver to be in the +1 form. No correlation was seen between the degradation and cation release profiles observed, and the P3O 9 3− anion was the highest released anionic species, which correlated well with the XRD and NMR studies. Overall, it was ascertained that using Ag2SO4 as a precursor, and producing compositions containing 3 and 5mol% Ag, the levels of silver ions released were within the acceptable cyto/biocompatible range. Springer Science+Business Media, LLC, 2007 Ahmed I. Division of Biomaterials and Tissue Engineering, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut Abou Neel E. Division of Biomaterials and Tissue Engineering, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut Valappil S. Division of Biomaterials and Tissue Engineering, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut Nazhat S. Division of Biomaterials and Tissue Engineering, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut Pickup D. School of Physical Sciences, University of Kent, CT2 7NH, Canterbury, UK aut Carta D. School of Physical Sciences, University of Kent, CT2 7NH, Canterbury, UK aut Carroll D. Department of Physics, University of Warwick, CV4 7AL, Coventry, UK aut Newport R. School of Physical Sciences, University of Kent, CT2 7NH, Canterbury, UK aut Smith M. Department of Physics, University of Warwick, CV4 7AL, Coventry, UK aut Knowles J. Division of Biomaterials and Tissue Engineering, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut Journal of Materials Science Springer US; http://www.springer-ny.com 42/23(2007-12-01), 9827-9835 0022-2461 42:23<9827 2007 42 10853 https://doi.org/10.1007/s10853-007-2008-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10853-007-2008-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ahmed I. Division of Biomaterials and Tissue Engineering, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut NATIONALLICENCE 700 1- Abou Neel E. Division of Biomaterials and Tissue Engineering, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut NATIONALLICENCE 700 1- Valappil S. Division of Biomaterials and Tissue Engineering, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut NATIONALLICENCE 700 1- Nazhat S. Division of Biomaterials and Tissue Engineering, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut NATIONALLICENCE 700 1- Pickup D. School of Physical Sciences, University of Kent, CT2 7NH, Canterbury, UK aut NATIONALLICENCE 700 1- Carta D. School of Physical Sciences, University of Kent, CT2 7NH, Canterbury, UK aut NATIONALLICENCE 700 1- Carroll D. Department of Physics, University of Warwick, CV4 7AL, Coventry, UK aut NATIONALLICENCE 700 1- Newport R. School of Physical Sciences, University of Kent, CT2 7NH, Canterbury, UK aut NATIONALLICENCE 700 1- Smith M. Department of Physics, University of Warwick, CV4 7AL, Coventry, UK aut NATIONALLICENCE 700 1- Knowles J. Division of Biomaterials and Tissue Engineering, Eastman Dental Institute, University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK aut NATIONALLICENCE 773 0- Journal of Materials Science Springer US; http://www.springer-ny.com 42/23(2007-12-01), 9827-9835 0022-2461 42:23<9827 2007 42 10853 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer