caa a22 4500 463232496 CHVBK 20180405153246.0 cr unu---uuuuu 170326e20071101xx s 000 0 eng 10.1007/s10853-007-1792-6 doi (NATIONALLICENCE)springer-10.1007/s10853-007-1792-6 Analysis of deformation coupled surface remodeling in porous biomaterials [Elektronische Daten] [Partha Ganguly, Franz-Josef Ulm] Surface remodeling of biological tissues through tissue growth or dissolution is deemed critical to their proper functioning, and is influenced by the deformation of the tissues during physiological activities. The present work attempts to develop a constitutive framework for deformation modulated surface remodeling of biological tissues. The framework is developed assuming finite deformation of the tissue, and the effect of deformation on the driving force for surface remodeling is determined from thermodynamic principles. The microscopic trends are upscaled to yield the remodeling-induced change in a macroscopic porous tissue. By way of application, the effect of deformation on the remodeling kinetics is determined for an incompressible elastic tissue. Depending on the ratio of the specific elastic stiffness and the specific Gibbs energy variation induced by the cell, the effect of deformation on the remodeling kinetics can be significant. It is found that both tensile and compressive deformation aid tissue dissolution (and dissuade growth). However, the magnitude of the effect is found to be different under tensile and compressive loadings, and critically depends on the reference frame used for the strain measurements. For Lagrangian strain measures (e.g., stretch, engineering strain), the increase in the dissolution kinetics per unit strain is higher under compressive loadings. On the other hand, for Eulerian strain measures (e.g., logarithmic or true strain), the effect of tensile loading on the dissolution kinetics is higher. This reinforces the need for proper reference frame definition for experimental strain measurements. Springer Science+Business Media, LLC, 2007 Ganguly Partha Schlumberger Doll Research, 02141, Cambridge, MA, USA aut Ulm Franz-Josef Massachusetts Institute of Technology, 77 Massachusetts Ave., 02139, Cambridge, MA, USA aut Journal of Materials Science Springer US; http://www.springer-ny.com 42/21(2007-11-01), 8873-8884 0022-2461 42:21<8873 2007 42 10853 https://doi.org/10.1007/s10853-007-1792-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10853-007-1792-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ganguly Partha Schlumberger Doll Research, 02141, Cambridge, MA, USA aut NATIONALLICENCE 700 1- Ulm Franz-Josef Massachusetts Institute of Technology, 77 Massachusetts Ave., 02139, Cambridge, MA, USA aut NATIONALLICENCE 773 0- Journal of Materials Science Springer US; http://www.springer-ny.com 42/21(2007-11-01), 8873-8884 0022-2461 42:21<8873 2007 42 10853 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer