caa a22 4500 463235193 CHVBK 20180405153254.0 cr unu---uuuuu 170326e20070601xx s 000 0 eng 10.1007/s10404-006-0138-z doi (NATIONALLICENCE)springer-10.1007/s10404-006-0138-z Enhancing microcantilever capability with integrated AC electroosmotic trapping [Elektronische Daten] [N. Islam, M. Lian, J. Wu] Microcantilevers are finding wide applications in detecting biochemical agents. However, their usage has been limited to highly concentrated samples to ensure sufficient deposition of agents onto cantilevers. A pre-concentration or enrichment step will expand their application range to more dilute, practical samples and real-time detection. This paper reports the integration of in-situ particle concentrators on microcantilevers. Only a thin metal layer on microcantilevers is required to generate microfluidic convection of particles from solution bulk onto microcantilever surfaces, greatly enriching local particle counts and enhancing sensitivity of the system. A working prototype is presented in the paper. Preliminary experiments concentrating latex particles were conducted and the particle concentration effect has been experimentally verified using AFM probes as microcantilevers. As ACEO concentrator has no dependence on particle properties, the method is expected to be applicable to bio-particles collection. Springer-Verlag, 2006 AC electroosmosis nationallicence Microfluidic nationallicence Particle trapping nationallicence Microcantilever nationallicence Islam N. Department of Electrical and Computer Engineering, The University of Tennessee, 37996, Knoxville, TN, USA aut Lian M. Department of Electrical and Computer Engineering, The University of Tennessee, 37996, Knoxville, TN, USA aut Wu J. Department of Electrical and Computer Engineering, The University of Tennessee, 37996, Knoxville, TN, USA aut Microfluidics and Nanofluidics Springer-Verlag 3/3(2007-06-01), 369-375 1613-4982 3:3<369 2007 3 10404 https://doi.org/10.1007/s10404-006-0138-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10404-006-0138-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Islam N. Department of Electrical and Computer Engineering, The University of Tennessee, 37996, Knoxville, TN, USA aut NATIONALLICENCE 700 1- Lian M. Department of Electrical and Computer Engineering, The University of Tennessee, 37996, Knoxville, TN, USA aut NATIONALLICENCE 700 1- Wu J. Department of Electrical and Computer Engineering, The University of Tennessee, 37996, Knoxville, TN, USA aut NATIONALLICENCE 773 0- Microfluidics and Nanofluidics Springer-Verlag 3/3(2007-06-01), 369-375 1613-4982 3:3<369 2007 3 10404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer