caa a22 4500 463235444 CHVBK 20180405153255.0 cr unu---uuuuu 170326e20070401xx s 000 0 eng 10.1007/s10404-006-0120-9 doi (NATIONALLICENCE)springer-10.1007/s10404-006-0120-9 Computational fluid dynamics analysis of microbubble formation in microfluidic flow-focusing devices [Elektronische Daten] [Michael Weber, Robin Shandas] Bubble formation in a microfluidic flow-focusing device is simulated using the volume-of-fluid approach to achieve a complete solution of the Navier-Stokes equations for both the gas and liquid phases. The results of the simulation show good agreement with previous experimental results. A detailed examination of the predicted pressure and velocity profiles from the simulation also provide further validation for the conclusions drawn previously with experimental results. The simulation results show the existence of two distinct modes of bubble formation. Simulations of systems an order of magnitude smaller than those investigated experimentally indicate that such reduced systems sizes are a viable approach that would result in much smaller bubble sizes. Springer-Verlag, 2006 Microfluidics nationallicence CFD nationallicence Bubble nationallicence Ultrasound nationallicence Flow-focuser nationallicence Weber Michael Department of Mechanical Engineering, University of Colorado, Boulder, CO, USA aut Shandas Robin Department of Mechanical Engineering, University of Colorado, Boulder, CO, USA aut Microfluidics and Nanofluidics Springer-Verlag 3/2(2007-04-01), 195-206 1613-4982 3:2<195 2007 3 10404 https://doi.org/10.1007/s10404-006-0120-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10404-006-0120-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Weber Michael Department of Mechanical Engineering, University of Colorado, Boulder, CO, USA aut NATIONALLICENCE 700 1- Shandas Robin Department of Mechanical Engineering, University of Colorado, Boulder, CO, USA aut NATIONALLICENCE 773 0- Microfluidics and Nanofluidics Springer-Verlag 3/2(2007-04-01), 195-206 1613-4982 3:2<195 2007 3 10404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer