caa a22 4500 463235479 CHVBK 20180405153255.0 cr unu---uuuuu 170326e20070401xx s 000 0 eng 10.1007/s10404-006-0117-4 doi (NATIONALLICENCE)springer-10.1007/s10404-006-0117-4 Simulations of complex particle transport in heterogeneous active liquids [Elektronische Daten] [Daphne Weihs, Michael Teitell, Thomas Mason] Thermal-fluctuation and external force-induced motion of particles provide mechanical and rheological information for viscoelastic liquids and soft solids. Although particle tracking is well-developed, analysis of particle trajectories in active heterogeneous materials, such as living cells, is usually not simple or straightforward. These trajectories are sometimes composed of several concurrent processes occurring simultaneously or episodically in a complex fluid. Here, we introduce simulations that generate 2-dimensional trajectories of probe transport in a viscous liquid as a tool for complex-trajectory analysis. These computer simulations illustrate cases that are physically relevant and highlight key features, such as spatial confinements or convective speeds, which can for example define a cell's internal structure and active transport along tubules or fibers. Comparison to experimental data will allow quantitative identification of various concurrent processes and understanding of their time dependence. We examine several well-defined cases of particle motion that occur in soft samples, including living cells, and present information from the analysis as well as new approaches for complex processes. Springer-Verlag, 2006 Bio-microrheology nationallicence Brownian motion nationallicence Particle tracking nationallicence Mean square displacement nationallicence Weihs Daphne Department of Pathology and Laboratory Medicine, University of California at Los Angeles, 90095, Los Angeles, CA, USA aut Teitell Michael Department of Pathology and Laboratory Medicine, University of California at Los Angeles, 90095, Los Angeles, CA, USA aut Mason Thomas California NanoSystems Institute, University of California at Los Angeles, 90095, Los Angeles, CA, USA aut Microfluidics and Nanofluidics Springer-Verlag 3/2(2007-04-01), 227-237 1613-4982 3:2<227 2007 3 10404 https://doi.org/10.1007/s10404-006-0117-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10404-006-0117-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Weihs Daphne Department of Pathology and Laboratory Medicine, University of California at Los Angeles, 90095, Los Angeles, CA, USA aut NATIONALLICENCE 700 1- Teitell Michael Department of Pathology and Laboratory Medicine, University of California at Los Angeles, 90095, Los Angeles, CA, USA aut NATIONALLICENCE 700 1- Mason Thomas California NanoSystems Institute, University of California at Los Angeles, 90095, Los Angeles, CA, USA aut NATIONALLICENCE 773 0- Microfluidics and Nanofluidics Springer-Verlag 3/2(2007-04-01), 227-237 1613-4982 3:2<227 2007 3 10404 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer