caa a22 4500 46323653X CHVBK 20180405153259.0 cr unu---uuuuu 170326e20071001xx s 000 0 eng 10.1007/s11240-007-9271-y doi (NATIONALLICENCE)springer-10.1007/s11240-007-9271-y Regulation of metabolite production by precursors and elicitors in liquid cultures of Hypericum perforatum [Elektronische Daten] [Xiao-Na Liu, Xiu-Qing Zhang, Shi-Xiang Zhang, Jun-She Sun] Four precursors (l-phenylalanine, l-tryptophan, cinnamic acid and emodin) and one signal elicitor (methyl jasmonate, MeJA) were added to liquid cultures of Hypericum perforatum L. to study their effect on production of hyperforin and hypericins (pseudohypericin and hypericin). The addition of l-phenylalanine (75 to 100mgl−1) enhanced production of hypericins, but hyperforin levels were decreased. Hypericin, pseudohypericin and hyperforin concentrations were all decreased when l-tryptophan (25 to 100mgl−1) was added to the medium. However, addition of l-tryptophan (50mgl−1) with MeJA (100μM) stimulated hyperforin production significantly (1.81-fold) and resulted in an increased biomass. Cinnamic acid (25, 50mgl−1) and emodin (1.0 to 10.0mgl−1) each enhanced hyperforin accumulation in H. perforatum, but did not affect accumulation of hypericins. Springer Science+Business Media B.V., 2007 Cinnamic acid nationallicence Emodin nationallicence Hyperforin nationallicence Hypericins nationallicence l -Phenylalanine nationallicence l -Tryptophan nationallicence BA : 6-Benzylaminopurine nationallicence DMF : N,N-dimethylformamide nationallicence DW : Dry weight nationallicence IAA : Indoleacetic acid nationallicence IBA : 3-Indolylbutyie nationallicence MeJA : Methyl jasmonate nationallicence Liu Xiao-Na College of Food Science and Nutritional Engineering, China Agricultural University, 17 Qinghua East Road, 100083, Beijing, People's Republic of China aut Zhang Xiu-Qing College of Food Science and Nutritional Engineering, China Agricultural University, 17 Qinghua East Road, 100083, Beijing, People's Republic of China aut Zhang Shi-Xiang College of Food Science and Nutritional Engineering, China Agricultural University, 17 Qinghua East Road, 100083, Beijing, People's Republic of China aut Sun Jun-She College of Food Science and Nutritional Engineering, China Agricultural University, 17 Qinghua East Road, 100083, Beijing, People's Republic of China aut Plant Cell, Tissue and Organ Culture Springer Netherlands 91/1(2007-10-01), 1-7 0167-6857 91:1<1 2007 91 11240 https://doi.org/10.1007/s11240-007-9271-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11240-007-9271-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Liu Xiao-Na College of Food Science and Nutritional Engineering, China Agricultural University, 17 Qinghua East Road, 100083, Beijing, People's Republic of China aut NATIONALLICENCE 700 1- Zhang Xiu-Qing College of Food Science and Nutritional Engineering, China Agricultural University, 17 Qinghua East Road, 100083, Beijing, People's Republic of China aut NATIONALLICENCE 700 1- Zhang Shi-Xiang College of Food Science and Nutritional Engineering, China Agricultural University, 17 Qinghua East Road, 100083, Beijing, People's Republic of China aut NATIONALLICENCE 700 1- Sun Jun-She College of Food Science and Nutritional Engineering, China Agricultural University, 17 Qinghua East Road, 100083, Beijing, People's Republic of China aut NATIONALLICENCE 773 0- Plant Cell, Tissue and Organ Culture Springer Netherlands 91/1(2007-10-01), 1-7 0167-6857 91:1<1 2007 91 11240 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer