caa a22 4500 46323703X CHVBK 20180405153301.0 cr unu---uuuuu 170326e20070801xx s 000 0 eng 10.1007/s11259-007-0029-0 doi (NATIONALLICENCE)springer-10.1007/s11259-007-0029-0 Effect of an Immunosuppressor (Dexamethasone) on Eperythrozoon Infection [Elektronische Daten] [C. Yuan, Z. Yang, J. Zhu, L. Cui, X. Hua] The aim was to study the relationship between the infection rate of Eperythrozoon suis and the status of the immune system. Four pigs with chronic eperythrozoonosis were divided into experimental and control groups. Immunosuppression of the experimental group was accomplished by injecting with high-dose glucocorticoid (dexamethasone) on 3 consecutive days. Microscopic examination of blood smears was performed to observe the change of infection rate after administration. The blood samples of each group were collected on day 7 after administration for half-nested PCR assay. The microscopic results showed that the infection rate of the experimental group rose distinctly by 40 h late and remained at 90% in the days following administration. No changes were observed in the control group. PCR results showed a single expected 250 bp fragment in each group, which validated the positive microscopic results. This study demonstrated the significant effect of dexamethasone (DEX) on Eperythrozoon infection. Springer Science + Business Media, Inc., 2007 Eperythrozoon nationallicence dexamethasone nationallicence infection rate nationallicence half-nested PCR nationallicence microscopic examination nationallicence E. suis : Eperythrozoon suis nationallicence DEX : dexamethasone nationallicence PCR : polymerase chain reaction nationallicence Yuan C. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, China aut Yang Z. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, China aut Zhu J. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, China aut Cui L. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, China aut Hua X. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, China aut Veterinary Research Communications Kluwer Academic Publishers 31/6(2007-08-01), 661-664 0165-7380 31:6<661 2007 31 11259 https://doi.org/10.1007/s11259-007-0029-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11259-007-0029-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yuan C. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, China aut NATIONALLICENCE 700 1- Yang Z. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, China aut NATIONALLICENCE 700 1- Zhu J. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, China aut NATIONALLICENCE 700 1- Cui L. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, China aut NATIONALLICENCE 700 1- Hua X. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, China aut NATIONALLICENCE 773 0- Veterinary Research Communications Kluwer Academic Publishers 31/6(2007-08-01), 661-664 0165-7380 31:6<661 2007 31 11259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer