caa a22 4500 463237145 CHVBK 20180405153301.0 cr unu---uuuuu 170326e20070801xx s 000 0 eng 10.1007/s11259-007-3566-7 doi (NATIONALLICENCE)springer-10.1007/s11259-007-3566-7 A Pilot Study to Assess the Feasibility of a Submaximal Exercise Test to Measure Individual Response to Cardiac Medication in Dogs with Acquired Heart Failure [Elektronische Daten] [L. Ferasin, S. Marcora] Exercise testing is not commonly used in canine medicine because of several limitations. The aim of this study was to investigate the suitability of a treadmill test to measure the exercise capacity of untrained canine cardiac patients and to measure some biological parameters that might reflect the tolerance of dogs with heart failure to submaximal exercise. The exercise capacity of seven dogs with naturally occurring heart failure was evaluated before the institution of cardiac medication and 7 days after the beginning of the study. An additional re-examination was requested after 28 days. The exercise test was performed on a motorized treadmill at three different speeds (0.5 m/s, 1.0 m/s and 1.5 m/s). The following parameters were measured at the end of each stage and after 20 min recovery: heart rate, rectal temperature, glucose, lactate, aspartate aminotransferase, creatine kinase, Pvo 2, Pvco 2, pH, haematocrit, bicarbonate, sodium, potassium and chloride. Serum cardiac troponin-I was also measured at the beginning of the test and at the end of the recovery period. Owners' perception reflected the ability of their dogs to exercise on the treadmill. Lactate level increased noticeably with the intensity of the exercise test, and its variation coincided with different exercise tolerance observed by the owners. Heart rate seemed to follow a similar trend in the few dogs presented in sinus rhythm. None of the remaining parameters appeared to be sensitive indicators of activity level in the dogs used in this study. The treadmill exercise test in dogs with acquired heart failure is feasible and might provide useful information for assessing individual response to cardiac medication. Lactate and heart rate seemed to reflect individual levels of exercise tolerance, although further studies are necessary to confirm the reliability and repeatability of this test. Springer Science + Business Media, Inc., 2007 exercise test nationallicence treadmill nationallicence heart failure nationallicence dogs nationallicence canine nationallicence cardiac therapy nationallicence pimobendan nationallicence furosemide nationallicence digoxin nationallicence AST : aspartate aminotransferase nationallicence CHF : congestive heart failure nationallicence CK : creatine kinase nationallicence ECG : electrocardiography nationallicence ET : exercise testing nationallicence NYHA : New York Heart Association nationallicence P v co 2 : venous carbon dioxide tension nationallicence P v o 2 : venous oxygen tension nationallicence V o 2 max : maximum oxygen consumption nationallicence Ferasin L. Department of Clinical Veterinary Science, University of Bristol, Langford, UK aut Marcora S. School of Sport, Health and Exercise Sciences, University of Wales-Bangor, Bangor, UK aut Veterinary Research Communications Kluwer Academic Publishers 31/6(2007-08-01), 725-737 0165-7380 31:6<725 2007 31 11259 https://doi.org/10.1007/s11259-007-3566-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11259-007-3566-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ferasin L. Department of Clinical Veterinary Science, University of Bristol, Langford, UK aut NATIONALLICENCE 700 1- Marcora S. School of Sport, Health and Exercise Sciences, University of Wales-Bangor, Bangor, UK aut NATIONALLICENCE 773 0- Veterinary Research Communications Kluwer Academic Publishers 31/6(2007-08-01), 725-737 0165-7380 31:6<725 2007 31 11259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer