caa a22 4500 463237390 CHVBK 20180405153302.0 cr unu---uuuuu 170326e20070401xx s 000 0 eng 10.1007/s11259-006-3432-z doi (NATIONALLICENCE)springer-10.1007/s11259-006-3432-z Metabolism of Methenolone Acetate in a Veal Calf [Elektronische Daten] [N. Van Hoof, D. Courtheyn, W. Gillis, J. Van Hende, C. Van Peteghem, M. Van de Wiele, S. Poelmans, H. Noppe, C. Van Poucke, E. Cobbaert, P. Vanthemse, H. De Brabander] The use of anabolic steroids has been banned in the European Union since 1981. In this study, the metabolism of the anabolic steroid methenolone acetate, was investigated in a male veal calf. After daily oral administration of methenolone acetate, three main metabolites were detected in both urine and faeces samples. Among these metabolites, α-methenolone was apparently the main one, but 1-methyl-5α-androstan-3,17-diol and 3α-hydroxy-1-methyl-5α-androstan-17-one were also observed. The parent compound was still detectable in faeces. As a consequence, abuse of methenolone acetate as growth promoter can be monitored by analysing urine and faeces samples. A few days after the last treatment, however, no metabolites were observed. α-Methenolone was detectable in urine until 5 days after the last treatment, but in faeces no metabolites were detectable after 3 days. Springer Science + Business Media, Inc., 2007 GC-MS nationallicence metabolism nationallicence methenolone acetate nationallicence GC-MS : gas chromatography-mass spectrometry nationallicence MSTFA : N-methyl-N-(trimethylsilyl)trifluoracetamide nationallicence HPLC : high-pressure liquid chromatography nationallicence TMS : trimethylsilyl nationallicence Van Hoof N. Research Group Veterinary Public Health and Zoonoses, Department of Veterinary Public Health and Food Safety, Laboratory of Chemical Analysis, Ghent University, Merelbeke aut Courtheyn D. Federal Food Laboratory, Gentbrugge aut Gillis W. Federal Agency for the Safety of the Food Chain, WTC III, Brussels aut Van Hende J. Research Group Veterinary Public Health and Zoonoses, Department of Veterinary Public Health and Food Safety, Laboratory of Chemical Analysis, Ghent University, Merelbeke aut Van Peteghem C. Faculty of Pharmaceutical Sciences, Laboratory of Food Analysis, Ghent University, Gent, Belgium aut Van de Wiele M. Federal Food Laboratory, Gentbrugge aut Poelmans S. Research Group Veterinary Public Health and Zoonoses, Department of Veterinary Public Health and Food Safety, Laboratory of Chemical Analysis, Ghent University, Merelbeke aut Noppe H. Research Group Veterinary Public Health and Zoonoses, Department of Veterinary Public Health and Food Safety, Laboratory of Chemical Analysis, Ghent University, Merelbeke aut Van Poucke C. Faculty of Pharmaceutical Sciences, Laboratory of Food Analysis, Ghent University, Gent, Belgium aut Cobbaert E. Federal Agency for the Safety of the Food Chain, WTC III, Brussels aut Vanthemse P. Federal Agency for the Safety of the Food Chain, WTC III, Brussels aut De Brabander H. Research Group Veterinary Public Health and Zoonoses, Department of Veterinary Public Health and Food Safety, Laboratory of Chemical Analysis, Ghent University, Merelbeke aut Veterinary Research Communications Kluwer Academic Publishers 31/3(2007-04-01), 259-272 0165-7380 31:3<259 2007 31 11259 https://doi.org/10.1007/s11259-006-3432-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11259-006-3432-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Van Hoof N. Research Group Veterinary Public Health and Zoonoses, Department of Veterinary Public Health and Food Safety, Laboratory of Chemical Analysis, Ghent University, Merelbeke aut NATIONALLICENCE 700 1- Courtheyn D. Federal Food Laboratory, Gentbrugge aut NATIONALLICENCE 700 1- Gillis W. Federal Agency for the Safety of the Food Chain, WTC III, Brussels aut NATIONALLICENCE 700 1- Van Hende J. Research Group Veterinary Public Health and Zoonoses, Department of Veterinary Public Health and Food Safety, Laboratory of Chemical Analysis, Ghent University, Merelbeke aut NATIONALLICENCE 700 1- Van Peteghem C. Faculty of Pharmaceutical Sciences, Laboratory of Food Analysis, Ghent University, Gent, Belgium aut NATIONALLICENCE 700 1- Van de Wiele M. Federal Food Laboratory, Gentbrugge aut NATIONALLICENCE 700 1- Poelmans S. Research Group Veterinary Public Health and Zoonoses, Department of Veterinary Public Health and Food Safety, Laboratory of Chemical Analysis, Ghent University, Merelbeke aut NATIONALLICENCE 700 1- Noppe H. Research Group Veterinary Public Health and Zoonoses, Department of Veterinary Public Health and Food Safety, Laboratory of Chemical Analysis, Ghent University, Merelbeke aut NATIONALLICENCE 700 1- Van Poucke C. Faculty of Pharmaceutical Sciences, Laboratory of Food Analysis, Ghent University, Gent, Belgium aut NATIONALLICENCE 700 1- Cobbaert E. Federal Agency for the Safety of the Food Chain, WTC III, Brussels aut NATIONALLICENCE 700 1- Vanthemse P. Federal Agency for the Safety of the Food Chain, WTC III, Brussels aut NATIONALLICENCE 700 1- De Brabander H. Research Group Veterinary Public Health and Zoonoses, Department of Veterinary Public Health and Food Safety, Laboratory of Chemical Analysis, Ghent University, Merelbeke aut NATIONALLICENCE 773 0- Veterinary Research Communications Kluwer Academic Publishers 31/3(2007-04-01), 259-272 0165-7380 31:3<259 2007 31 11259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer