caa a22 4500 463245199 CHVBK 20180405153323.0 cr unu---uuuuu 170326e20070801xx s 000 0 eng 10.1007/s00422-007-0161-5 doi (NATIONALLICENCE)springer-10.1007/s00422-007-0161-5 Branching dendrites with resonant membrane: a "sum-over-trips” approach [Elektronische Daten] [S. Coombes, Y. Timofeeva, C. Svensson, G. Lord, K. Josić, S. Cox, C. Colbert] Dendrites form the major components of neurons. They are complex branching structures that receive and process thousands of synaptic inputs from other neurons. It is well known that dendritic morphology plays an important role in the function of dendrites. Another important contribution to the response characteristics of a single neuron comes from the intrinsic resonant properties of dendritic membrane. In this paper we combine the effects of dendritic branching and resonant membrane dynamics by generalising the "sum-over-trips” approach (Abbott etal. in Biol Cybernetics 66, 49-60 1991). To illustrate how this formalism can shed light on the role of architecture and resonances in determining neuronal output we consider dual recording and reconstruction data from a rat CA1 hippocampal pyramidal cell. Specifically we explore the way in which an I h current contributes to a voltage overshoot at the soma. Springer-Verlag, 2007 Dendrites nationallicence Quasi-active membrane nationallicence "Sum-over-trips” nationallicence Cable theory nationallicence Coombes S. Department of Mathematical Sciences, University of Nottingham, NG7 2RD, Nottingham, UK aut Timofeeva Y. Department of Mathematical Sciences, University of Nottingham, NG7 2RD, Nottingham, UK aut Svensson C. Department of Mathematical Sciences, University of Nottingham, NG7 2RD, Nottingham, UK aut Lord G. Department of Mathematics, Heriot-Watt University, EH14 4AS, Edinburgh, UK aut Josić K. Department of Mathematics, University of Houston, 77204-3008, Houston, TX, USA aut Cox S. Computational and Applied Mathematics, Rice University, 77005, Houston, Texas, USA aut Colbert C. Biology and Biochemistry, University of Houston, 77204-5001, Houston, TX, USA aut Biological Cybernetics Springer-Verlag 97/2(2007-08-01), 137-149 0340-1200 97:2<137 2007 97 422 https://doi.org/10.1007/s00422-007-0161-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00422-007-0161-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Coombes S. Department of Mathematical Sciences, University of Nottingham, NG7 2RD, Nottingham, UK aut NATIONALLICENCE 700 1- Timofeeva Y. Department of Mathematical Sciences, University of Nottingham, NG7 2RD, Nottingham, UK aut NATIONALLICENCE 700 1- Svensson C. Department of Mathematical Sciences, University of Nottingham, NG7 2RD, Nottingham, UK aut NATIONALLICENCE 700 1- Lord G. Department of Mathematics, Heriot-Watt University, EH14 4AS, Edinburgh, UK aut NATIONALLICENCE 700 1- Josić K. Department of Mathematics, University of Houston, 77204-3008, Houston, TX, USA aut NATIONALLICENCE 700 1- Cox S. Computational and Applied Mathematics, Rice University, 77005, Houston, Texas, USA aut NATIONALLICENCE 700 1- Colbert C. Biology and Biochemistry, University of Houston, 77204-5001, Houston, TX, USA aut NATIONALLICENCE 773 0- Biological Cybernetics Springer-Verlag 97/2(2007-08-01), 137-149 0340-1200 97:2<137 2007 97 422 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer