caa a22 4500 463245571 CHVBK 20180405153324.0 cr unu---uuuuu 170326e20070201xx s 000 0 eng 10.1007/s00422-006-0111-7 doi (NATIONALLICENCE)springer-10.1007/s00422-006-0111-7 A comparative analysis of multi-conductance neuronal models in silico [Elektronische Daten] [Stephen DeWeerth, Michael Reid, Edgar Brown, Robert Butera Jr.] We demonstrate that a previously presented flexible silicon-neuron architecture can implement three disparate conductance-based neuron models with both fast and slow dynamics. By exploiting the real-time nature of this physical implementation, we mapped the model dynamics across a large region of parameter space. We also found that two of these dynamically different models represent points in a contiguous bursting space that spans between the two models. By systematically varying the model parameters, we also found that multiple, diverse trajectories in parameter space connected the two canonical bursting points. In addition, we found that the combination of parameter values keeps the neuron in the bursting region. These findings demonstrate the usefulness of the silicon-neuron architecture as a neural-modeling tool and illustrate its versatility as a platform for a multi-behavioral neuron that resembles its living analog. Springer-Verlag, 2006 DeWeerth Stephen Laboratory for Neuroengineering, Georgia Institute of Technology, 30332, Atlanta, GA, USA aut Reid Michael Laboratory for Neuroengineering, Georgia Institute of Technology, 30332, Atlanta, GA, USA aut Brown Edgar Laboratory for Neuroengineering, Georgia Institute of Technology, 30332, Atlanta, GA, USA aut Butera Jr. Robert Laboratory for Neuroengineering, Georgia Institute of Technology, 30332, Atlanta, GA, USA aut Biological Cybernetics Springer-Verlag 96/2(2007-02-01), 181-194 0340-1200 96:2<181 2007 96 422 https://doi.org/10.1007/s00422-006-0111-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00422-006-0111-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- DeWeerth Stephen Laboratory for Neuroengineering, Georgia Institute of Technology, 30332, Atlanta, GA, USA aut NATIONALLICENCE 700 1- Reid Michael Laboratory for Neuroengineering, Georgia Institute of Technology, 30332, Atlanta, GA, USA aut NATIONALLICENCE 700 1- Brown Edgar Laboratory for Neuroengineering, Georgia Institute of Technology, 30332, Atlanta, GA, USA aut NATIONALLICENCE 700 1- Butera Jr Robert Laboratory for Neuroengineering, Georgia Institute of Technology, 30332, Atlanta, GA, USA aut NATIONALLICENCE 773 0- Biological Cybernetics Springer-Verlag 96/2(2007-02-01), 181-194 0340-1200 96:2<181 2007 96 422 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer