caa a22 4500 463249259 CHVBK 20180405153335.0 cr unu---uuuuu 170326e20070601xx s 000 0 eng 10.1007/s11130-007-0042-z doi (NATIONALLICENCE)springer-10.1007/s11130-007-0042-z The Influence of Maca ( Lepidium meyenii ) on Antioxidant Status, Lipid and Glucose Metabolism in Rat [Elektronische Daten] [ROSTISLAV VEČEŘA, JAN OROLIN, NINA ŠKOTTOVÁ, LUDMILA KAZDOVÁ, OLENA OLIYARNIK, JITKA ULRICHOVÁ, VILÍM ŠIMÁNEK] This work focused on the effect of maca on lipid, anti-oxidative, and glucose parameters in hereditary hypertriglyceridemic (HHTg) rat. Maca (1%) was administred to rats as a part of a high-sucrose diet (HSD) for 2 weeks. Rosiglitazone (0.02%) was used as a positive control. Maca significantly decreased the levels of VLDL (very low density lipoproteins), LDL (low density lipoproteins), and total cholesterol, and also the level of TAG (triacylglycerols) in the plasma, VLDL, and liver. Maca, as well as rosiglitazone, significantly improved glucose tolerance, as the decrease of AUC (area under the curve) of glucose showed, and lowered levels of glucose in blood. The activity of SOD (superoxide dismutase) in the liver, the GPX (glutathione peroxidase) in the blood, and the level of GSH (glutathione) in liver increased in all cases significantly. Results demonstrate that maca seems to be promising for a positive influence on chronic human diseases (characterized by atherogenous lipoprotein profile, aggravated antioxidative status, and impaired glucose tolerance), and their prevention. Springer Science+Business Media, Inc., 2007 Cholesterol nationallicence Dietary supplement nationallicence Lipoproteins nationallicence Maca nationallicence Triacylglycerols nationallicence VEČEŘA ROSTISLAV Institute of Pharmacology, Medical Faculty, Palacký University, Hněvotínská 3, 775 15, Olomouc, Czech Republic aut OROLIN JAN Institute of Pharmacology, Medical Faculty, Palacký University, Hněvotínská 3, 775 15, Olomouc, Czech Republic aut ŠKOTTOVÁ NINA Institute of Pharmacology, Medical Faculty, Palacký University, Hněvotínská 3, 775 15, Olomouc, Czech Republic aut KAZDOVÁ LUDMILA Institute for Clinical and Experimental Medicine, Vídeňská 1958/9, 140 21, Praha 4, Czech Republic aut OLIYARNIK OLENA Institute for Clinical and Experimental Medicine, Vídeňská 1958/9, 140 21, Praha 4, Czech Republic aut ULRICHOVÁ JITKA Institute of Medical Chemistry, Medical Faculty, Palacký University, Hněvotínská 3, 775 15, Olomouc, Czech Republic aut ŠIMÁNEK VILÍM Institute of Medical Chemistry, Medical Faculty, Palacký University, Hněvotínská 3, 775 15, Olomouc, Czech Republic aut Plant Foods for Human Nutrition Kluwer Academic Publishers-Plenum Publishers; http://www.springer-ny.com 62/2(2007-06-01), 59-63 0921-9668 62:2<59 2007 62 11130 https://doi.org/10.1007/s11130-007-0042-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11130-007-0042-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- VEČEŘA ROSTISLAV Institute of Pharmacology, Medical Faculty, Palacký University, Hněvotínská 3, 775 15, Olomouc, Czech Republic aut NATIONALLICENCE 700 1- OROLIN JAN Institute of Pharmacology, Medical Faculty, Palacký University, Hněvotínská 3, 775 15, Olomouc, Czech Republic aut NATIONALLICENCE 700 1- ŠKOTTOVÁ NINA Institute of Pharmacology, Medical Faculty, Palacký University, Hněvotínská 3, 775 15, Olomouc, Czech Republic aut NATIONALLICENCE 700 1- KAZDOVÁ LUDMILA Institute for Clinical and Experimental Medicine, Vídeňská 1958/9, 140 21, Praha 4, Czech Republic aut NATIONALLICENCE 700 1- OLIYARNIK OLENA Institute for Clinical and Experimental Medicine, Vídeňská 1958/9, 140 21, Praha 4, Czech Republic aut NATIONALLICENCE 700 1- ULRICHOVÁ JITKA Institute of Medical Chemistry, Medical Faculty, Palacký University, Hněvotínská 3, 775 15, Olomouc, Czech Republic aut NATIONALLICENCE 700 1- ŠIMÁNEK VILÍM Institute of Medical Chemistry, Medical Faculty, Palacký University, Hněvotínská 3, 775 15, Olomouc, Czech Republic aut NATIONALLICENCE 773 0- Plant Foods for Human Nutrition Kluwer Academic Publishers-Plenum Publishers; http://www.springer-ny.com 62/2(2007-06-01), 59-63 0921-9668 62:2<59 2007 62 11130 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer