caa a22 4500 463249267 CHVBK 20180405153335.0 cr unu---uuuuu 170326e20070601xx s 000 0 eng 10.1007/s11130-007-0045-9 doi (NATIONALLICENCE)springer-10.1007/s11130-007-0045-9 Antioxidative and Anticancer Activity of Extracts of Cherry ( Prunus serrulata var. spontanea ) Blossoms [Elektronische Daten] [Bo-Bae Lee, Mi-Ran Cha, Soo-Yeon Kim, Eunju Park, Hae-Ryong Park, Seung-Cheol Lee] Organic solvent (methanol, ethanol, and acetone) extracts and water extracts of cherry (Prunus serrulata var. spontanea) blossoms were prepared, and antioxidant activities of the extracts were evaluated. Methanolic CBE (100μg/ml) showed the highest total phenol content (104.30μM), radical scavenging activity (34.2%), and reducing power (0.391). The effect of CBE on DNA damage induced by H2O2 in human leukocytes was evaluated by Comet assay. All CBE was a potent dose dependent inhibitor of DNA damage induced by 200μM of H2O2, methanolic CBE showed the most strong inhibition activity. The methanolic CBE of 500μg/ml showed 38.8% inhibition against growth of human colon cancer cell line HT-29. These results indicated that cherry blossoms could provide valuable bioactive materials. Springer Science+Business Media, Inc., 2007 Prunus serrulata var. spontanea nationallicence Extract nationallicence Antioxidant nationallicence Anticancer nationallicence Lee Bo-Bae Department of Food Science and Biotechnology, Kyungnam University, 631-701, Masan, Republic of Korea aut Cha Mi-Ran Department of Food Science and Biotechnology, Kyungnam University, 631-701, Masan, Republic of Korea aut Kim Soo-Yeon Department of Food and Nutrition, Kyungnam University, 631-701, Masan, Republic of Korea aut Park Eunju Department of Food and Nutrition, Kyungnam University, 631-701, Masan, Republic of Korea aut Park Hae-Ryong Department of Food Science and Biotechnology, Kyungnam University, 631-701, Masan, Republic of Korea aut Lee Seung-Cheol Department of Food Science and Biotechnology, Kyungnam University, 631-701, Masan, Republic of Korea aut Plant Foods for Human Nutrition Kluwer Academic Publishers-Plenum Publishers; http://www.springer-ny.com 62/2(2007-06-01), 79-84 0921-9668 62:2<79 2007 62 11130 https://doi.org/10.1007/s11130-007-0045-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11130-007-0045-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lee Bo-Bae Department of Food Science and Biotechnology, Kyungnam University, 631-701, Masan, Republic of Korea aut NATIONALLICENCE 700 1- Cha Mi-Ran Department of Food Science and Biotechnology, Kyungnam University, 631-701, Masan, Republic of Korea aut NATIONALLICENCE 700 1- Kim Soo-Yeon Department of Food and Nutrition, Kyungnam University, 631-701, Masan, Republic of Korea aut NATIONALLICENCE 700 1- Park Eunju Department of Food and Nutrition, Kyungnam University, 631-701, Masan, Republic of Korea aut NATIONALLICENCE 700 1- Park Hae-Ryong Department of Food Science and Biotechnology, Kyungnam University, 631-701, Masan, Republic of Korea aut NATIONALLICENCE 700 1- Lee Seung-Cheol Department of Food Science and Biotechnology, Kyungnam University, 631-701, Masan, Republic of Korea aut NATIONALLICENCE 773 0- Plant Foods for Human Nutrition Kluwer Academic Publishers-Plenum Publishers; http://www.springer-ny.com 62/2(2007-06-01), 79-84 0921-9668 62:2<79 2007 62 11130 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer