caa a22 4500 463251199 CHVBK 20180405153340.0 cr unu---uuuuu 170326e20070201xx s 000 0 eng 10.1007/s10803-006-0157-3 doi (NATIONALLICENCE)springer-10.1007/s10803-006-0157-3 MMR-Vaccine and Regression in Autism Spectrum Disorders: Negative Results Presented from Japan [Elektronische Daten] [Tokio Uchiyama, Michiko Kurosawa, Yutaka Inaba] It has been suggested that the measles, mumps, and rubella vaccine (MMR) is a cause of regressive autism. As MMR was used in Japan only between 1989 and 1993, this time period affords a natural experiment to examine this hypothesis. Data on 904 patients with autism spectrum disorders (ASD) were analyzed. During the period of MMR usage no significant difference was found in the incidence of regression between MMR-vaccinated children and non-vaccinated children. Among the proportion and incidence of regression across the three MMR-program-related periods (before, during and after MMR usage), no significant difference was found between those who had received MMR and those who had not. Moreover, the incidence of regression did not change significantly across the three periods. Springer Science+Business Media, Inc., 2006 MMR nationallicence Autism nationallicence ASD nationallicence Regression nationallicence Uchiyama Tokio Department of Human Welfare, Otsuma Women's University, 2-7-1, Karakida, 206-8540, Tama-city, Tokyo, Japan aut Kurosawa Michiko Department of Epidemiology and Environmental Health, Juntendo University School of Medicine, Tokyo, Japan aut Inaba Yutaka Department of Epidemiology and Environmental Health, Juntendo University School of Medicine, Tokyo, Japan aut Journal of Autism and Developmental Disorders Kluwer Academic Publishers-Plenum Publishers; http://www.springer-ny.com 37/2(2007-02-01), 210-217 0162-3257 37:2<210 2007 37 10803 https://doi.org/10.1007/s10803-006-0157-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10803-006-0157-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Uchiyama Tokio Department of Human Welfare, Otsuma Women's University, 2-7-1, Karakida, 206-8540, Tama-city, Tokyo, Japan aut NATIONALLICENCE 700 1- Kurosawa Michiko Department of Epidemiology and Environmental Health, Juntendo University School of Medicine, Tokyo, Japan aut NATIONALLICENCE 700 1- Inaba Yutaka Department of Epidemiology and Environmental Health, Juntendo University School of Medicine, Tokyo, Japan aut NATIONALLICENCE 773 0- Journal of Autism and Developmental Disorders Kluwer Academic Publishers-Plenum Publishers; http://www.springer-ny.com 37/2(2007-02-01), 210-217 0162-3257 37:2<210 2007 37 10803 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer