caa a22 4500 463255631 CHVBK 20180405153354.0 cr unu---uuuuu 170326e20070901xx s 000 0 eng 10.1007/s00277-007-0296-4 doi (NATIONALLICENCE)springer-10.1007/s00277-007-0296-4 Epidemiology, features and outcome of pain in patients with advanced hematological malignancies followed in a home care program: an Italian survey [Elektronische Daten] [Pasquale Niscola, Claudio Cartoni, Claudio Romani, Gregorio Brunetti, Gianna D'Elia, Luca Cupelli, Andrea Tendas, Paolo de Fabritiis, Franco Mandelli, Robin Foà] We report on epidemiology, features, outcome, and domiciliary management of pain in patients with advanced hematological malignancies followed by an experienced hospital-based home care (HC) team. Out of 469 patients, 244 (52%) experienced a total of 284 pain syndromes. Pain intensity was rated from mild to moderate in 31% and from moderate to severe in 69% of them. The diagnosed pain mechanisms were deep somatic in 56%, superficial somatic in 15%, visceral 14%, mixed 8%, and neuropathic in 7% of pain syndromes, respectively. Incident pain was observed in 38% of all pain syndromes. In every diagnostic group, deep somatic pain was prevalent. Moreover, 85% of visceral pain syndromes were observed in patients affected by non-Hodgkin's lymphoma (NHL). In addition, out of 284 pain syndromes, 150 (51%) were caused by bone involvement. The most frequent recognized pain provocative mechanisms were bone marrow expansions, osteolysis, lymph node enlargement, and mucositis. In our experience, an approach based on the association of causal therapies and analgesics allows optimal control of most pain syndromes. Therefore, pain is a major problem in patients affected by advanced hematological malignancies, and its management can be effective and feasible when carried out by a skilled HC team. Springer-Verlag, 2007 Home care nationallicence Pain nationallicence Hematological malignancies nationallicence Niscola Pasquale Haematology Division, Tor Vergata University, Sant'Eugenio Hospital, Rome, Italy aut Cartoni Claudio Human Biopathology and Haematology Department, "La Sapienza” University, Rome, Italy aut Romani Claudio Armando Businco Cancer Centre, Cagliari, Italy aut Brunetti Gregorio Human Biopathology and Haematology Department, "La Sapienza” University, Rome, Italy aut D'Elia Gianna Human Biopathology and Haematology Department, "La Sapienza” University, Rome, Italy aut Cupelli Luca Haematology Division, Tor Vergata University, Sant'Eugenio Hospital, Rome, Italy aut Tendas Andrea Haematology Division, Tor Vergata University, Sant'Eugenio Hospital, Rome, Italy aut de Fabritiis Paolo Haematology Division, Tor Vergata University, Sant'Eugenio Hospital, Rome, Italy aut Mandelli Franco Human Biopathology and Haematology Department, "La Sapienza” University, Rome, Italy aut Foà Robin Human Biopathology and Haematology Department, "La Sapienza” University, Rome, Italy aut Annals of Hematology Springer-Verlag 86/9(2007-09-01), 671-676 0939-5555 86:9<671 2007 86 277 https://doi.org/10.1007/s00277-007-0296-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00277-007-0296-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Niscola Pasquale Haematology Division, Tor Vergata University, Sant'Eugenio Hospital, Rome, Italy aut NATIONALLICENCE 700 1- Cartoni Claudio Human Biopathology and Haematology Department, "La Sapienza” University, Rome, Italy aut NATIONALLICENCE 700 1- Romani Claudio Armando Businco Cancer Centre, Cagliari, Italy aut NATIONALLICENCE 700 1- Brunetti Gregorio Human Biopathology and Haematology Department, "La Sapienza” University, Rome, Italy aut NATIONALLICENCE 700 1- D'Elia Gianna Human Biopathology and Haematology Department, "La Sapienza” University, Rome, Italy aut NATIONALLICENCE 700 1- Cupelli Luca Haematology Division, Tor Vergata University, Sant'Eugenio Hospital, Rome, Italy aut NATIONALLICENCE 700 1- Tendas Andrea Haematology Division, Tor Vergata University, Sant'Eugenio Hospital, Rome, Italy aut NATIONALLICENCE 700 1- de Fabritiis Paolo Haematology Division, Tor Vergata University, Sant'Eugenio Hospital, Rome, Italy aut NATIONALLICENCE 700 1- Mandelli Franco Human Biopathology and Haematology Department, "La Sapienza” University, Rome, Italy aut NATIONALLICENCE 700 1- Foà Robin Human Biopathology and Haematology Department, "La Sapienza” University, Rome, Italy aut NATIONALLICENCE 773 0- Annals of Hematology Springer-Verlag 86/9(2007-09-01), 671-676 0939-5555 86:9<671 2007 86 277 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer