caa a22 4500 46325564X CHVBK 20180405153354.0 cr unu---uuuuu 170326e20070901xx s 000 0 eng 10.1007/s00277-007-0284-8 doi (NATIONALLICENCE)springer-10.1007/s00277-007-0284-8 Physician perceptions and preferences in the treatment of acquired immunodeficiency syndrome (AIDS)-related lymphoma [Elektronische Daten] [Matthew Cheung, Kevin Imrie, Heather Leitch, Laura Park-Wyllie, Rena Buckstein, Tony Antoniou, Mona Loutfy] The optimal management of acquired immunodeficiency syndrome-related lymphoma (ARL) in the era of combination antiretroviral therapy (cART) is unclear. We administered a survey to determine physician preferences and perceptions in the management of ARL and to assess the variability in treatment in Canada. Of 196 lymphoma-treating physicians, 117 (63%) responded. The majority of respondents (98%) had a positive attitude towards the treatment of ARL. Most physicians (66%) recommended the concomitant use of cART in the care of their patients with ARL, and a majority (86%) recommended CHOP-like regimens (cyclophosphamide, doxorubicin, vincristine, and prednisone) to form the backbone of chemotherapy. The addition of rituximab was preferred by 43% of physicians, while 39% and 18% would either not use rituximab or were unsure of the agent's role, respectively. In logistic regression analysis, use of rituximab was predicted only by location of practice (province); physicians from the province of British Colombia were much more likely to administer rituximab than practitioners from Ontario (odds ratio 41.8; 95% confidence interval 7.44-235.1, p < 0.001). In the current cART era, physicians have a positive attitude towards the treatment of ARL. The majority prefer to use cART in combination with CHOP for ARL. The use and perceived benefit of rituximab may be influenced by interprovincial formulary differences and regional variation in guideline recommendations. Springer-Verlag, 2007 AIDS-related lymphoma nationallicence Non-Hodgkin's lymphoma nationallicence Diffuse large B cell lymphoma nationallicence Human immunodeficiency virus nationallicence Antiretroviral therapy nationallicence Chemotherapy nationallicence Rituximab nationallicence Survey methodology nationallicence Cheung Matthew Department of Medicine, Division of Hematology/Medical Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada aut Imrie Kevin Department of Medicine, Division of Hematology/Medical Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada aut Leitch Heather Department of Medicine, Division of Hematology, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada aut Park-Wyllie Laura Department of Family and Community Medicine, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada aut Buckstein Rena Department of Medicine, Division of Hematology/Medical Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada aut Antoniou Tony Department of Family and Community Medicine, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada aut Loutfy Mona Department of Medicine, Division of Infectious Diseases, Maple Leaf Medical Clinic, University of Toronto, Toronto, ON, Canada aut Annals of Hematology Springer-Verlag 86/9(2007-09-01), 631-638 0939-5555 86:9<631 2007 86 277 https://doi.org/10.1007/s00277-007-0284-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00277-007-0284-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cheung Matthew Department of Medicine, Division of Hematology/Medical Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Imrie Kevin Department of Medicine, Division of Hematology/Medical Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Leitch Heather Department of Medicine, Division of Hematology, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada aut NATIONALLICENCE 700 1- Park-Wyllie Laura Department of Family and Community Medicine, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Buckstein Rena Department of Medicine, Division of Hematology/Medical Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Antoniou Tony Department of Family and Community Medicine, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Loutfy Mona Department of Medicine, Division of Infectious Diseases, Maple Leaf Medical Clinic, University of Toronto, Toronto, ON, Canada aut NATIONALLICENCE 773 0- Annals of Hematology Springer-Verlag 86/9(2007-09-01), 631-638 0939-5555 86:9<631 2007 86 277 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer