caa a22 4500 465734235 CHVBK 20180323111750.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF01050399 doi (NATIONALLICENCE)springer-10.1007/BF01050399 Efficient synthesis of α(2-8)-linked N -acetyl and N -glycolylneuraminic acid disaccharides from colominic acid [Elektronische Daten] [René Roy, Robert Pon] Controlled acid hydrolysis of poly-α(2,8)-linked homopolymers ofN-acetylneuraminic acid (colominic acid) and its homologous poly-N-glycolylneuraminic acid afforded high yields of the corresponding disaccharides useful in block synthesis of disialylated gangliosides. The poly-N-glycolylanalog was derived from de-N-acetylated colominic acid by two different reaction sequences. The first one involved reaction with acetoxyacetyl chloride followed by de-O-acetylation. The second and most interesting one requiredN-acryloylation and reductive ozonolysis. Glycoconjugate Journal, 1990 colominic acid nationallicence N-glycolyneuraminic acid nationallicence Hanganutziu-Deicher antigen nationallicence sialyloligosaccharides nationallicence Roy René Department of Chemistry, University of Ottawa, K1N6N5, Ottawa, Ontario, Canada aut Pon Robert Department of Chemistry, University of Ottawa, K1N6N5, Ottawa, Ontario, Canada aut Glycoconjugate Journal Kluwer Academic Publishers 7/1(1990-01-01), 3-12 0282-0080 7:1<3 1990 7 10719 https://doi.org/10.1007/BF01050399 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01050399 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Roy René Department of Chemistry, University of Ottawa, K1N6N5, Ottawa, Ontario, Canada aut NATIONALLICENCE 700 1- Pon Robert Department of Chemistry, University of Ottawa, K1N6N5, Ottawa, Ontario, Canada aut NATIONALLICENCE 773 0- Glycoconjugate Journal Kluwer Academic Publishers 7/1(1990-01-01), 3-12 0282-0080 7:1<3 1990 7 10719 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer