caa a22 4500 465735061 CHVBK 20180323111752.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00167070 doi (NATIONALLICENCE)springer-10.1007/BF00167070 Paraneoplastic cerebellar degeneration associated with multiple myeloma —3.4 years follow up [Elektronische Daten] [Sevket Akpinar, Önder Berk, Levent Karaca] Summary: A 57 year old female patient demonstrated subacute generalized cerebellar symptoms and the investigations which were done exhibited that the clinical picture was due to the remote effect of multiple myeloma. In this case of paraneoplastic cerebellar degeneration, MRI showed cerebellar vermian atrophy when the brain CT scan was negative. Diagnosis of multiple myeloma was possible only on about the 17th month of the illness when monoclonal gammapathy-IgG in serum of the patient and abnormal plasma cells of 13% in her bone marrow biopsy were exhibited. Bence-Jones proteinuria with kappa light chain was found in the 3.4th year of the illness. Paraneoplastic cerebellar degeneration disabled the patient in 3-4 months and remained as an irreversible process during the 3.4 years in which she was followed until her death. Chemotherapy for multiple myeloma did not affect the cerebellar syndrome. Kluwer Academic Publishers, 1990 paraneoplastic cerebellar degeneration nationallicence multiple myeloma nationallicence Akpinar Sevket Department of Neurology, Gülhane Military Medical Academy and Medical Faculty, 06018, Etlik-Ankara, Turkey aut Berk Önder Department of Oncology, Gülhane Military Medical Academy and Medical Faculty, Ankara, Turkey aut Karaca Levent Department of Biochemistry, Gülhane Military Medical Academy and Medical Faculty, Ankara, Turkey aut Journal of Neuro-Oncology Kluwer Academic Publishers 9/1(1990-08-01), 63-68 0167-594X 9:1<63 1990 9 11060 https://doi.org/10.1007/BF00167070 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00167070 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Akpinar Sevket Department of Neurology, Gülhane Military Medical Academy and Medical Faculty, 06018, Etlik-Ankara, Turkey aut NATIONALLICENCE 700 1- Berk Önder Department of Oncology, Gülhane Military Medical Academy and Medical Faculty, Ankara, Turkey aut NATIONALLICENCE 700 1- Karaca Levent Department of Biochemistry, Gülhane Military Medical Academy and Medical Faculty, Ankara, Turkey aut NATIONALLICENCE 773 0- Journal of Neuro-Oncology Kluwer Academic Publishers 9/1(1990-08-01), 63-68 0167-594X 9:1<63 1990 9 11060 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer