caa a22 4500 465735096 CHVBK 20180323111752.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00167066 doi (NATIONALLICENCE)springer-10.1007/BF00167066 Alkaline phosphatase level in CSF in various brain tumors and pulmonary carcinomatous meningitis [Elektronische Daten] [Yair Lampl, Yvonne Paniri, Yechiel Eshel, Ida Sarova-Pincha] Summary: Twenty-six patients with various brain tumors or carcinomatous meningitis were examined for alkaline phosphatase (ALP) in the cerebrospinal fluid. ALP enzyme levels were compared with the respective levels in control groups of 75 patients with epilepsy, stroke, bacterial and viral meningitis and intervertebral disc prolapse. Extremely high ALP levels in CSF (9516 µ/l, 1425 µ/l, and 871 µ/l) were found in patients with pulmonary carcinomatous meningitis. Among all other patients with brain tumors, ALP levels in CSF were in the normal range. Examination of ALP in serum yielded normal results in all patients. In patients with pulmonary carcinomatous meningitis, the enzyme level in CSF was examined during various stages of radiotherapy and chemotherapy. Decreased ALP enzyme level was found during treatment followed by recurring rising levels a month after the treatment coinciding with clinical relapse. No correlation was found between the level of ALP enzyme and the biochemical and cellular content of the CSF during the various stages of treatment. Kluwer Academic Publishers, 1990 alkaline phosphatase nationallicence cerebrospinal fluid nationallicence brain tumor nationallicence carcinomatous meningitis nationallicence Lampl Yair Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler Faculty of Medicine, Israel aut Paniri Yvonne Department of Chemical Laboratory, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler Faculty of Medicine, Israel aut Eshel Yechiel Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler Faculty of Medicine, Israel aut Sarova-Pincha Ida Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler Faculty of Medicine, Israel aut Journal of Neuro-Oncology Kluwer Academic Publishers 9/1(1990-08-01), 35-40 0167-594X 9:1<35 1990 9 11060 https://doi.org/10.1007/BF00167066 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00167066 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lampl Yair Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler Faculty of Medicine, Israel aut NATIONALLICENCE 700 1- Paniri Yvonne Department of Chemical Laboratory, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler Faculty of Medicine, Israel aut NATIONALLICENCE 700 1- Eshel Yechiel Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler Faculty of Medicine, Israel aut NATIONALLICENCE 700 1- Sarova-Pincha Ida Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler Faculty of Medicine, Israel aut NATIONALLICENCE 773 0- Journal of Neuro-Oncology Kluwer Academic Publishers 9/1(1990-08-01), 35-40 0167-594X 9:1<35 1990 9 11060 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer