caa a22 4500 465735134 CHVBK 20180323111752.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00167069 doi (NATIONALLICENCE)springer-10.1007/BF00167069 High-dose thiotepa with autologous bone marrow rescue in recurrent malignant oligodendroglioma: A case report [Elektronische Daten] [Ulla Saarinen, Helena Pihko, Anne Mäkipernaa] High-dose thiotepa with autologous bone marrow rescue is a new and promising treatment modality in several kinds of solid tumors. We used this regimen in a pediatric patient who had the third recurrence of his malignant oligodendroglioma of brain that developed during ‘8 in 1' chemotherapy. We achieved complete response after a total dose of 1125 mg/m2 of intravenous thiotepa. Good penetration into the CNS renders thiotepa potentially useful for chemosensitive brain tumors, and one course of high-dose thiotepa can be administered with acceptable toxicity by utilizing autologous bone marrow rescue. Kluwer Academic Publishers, 1990 autologous bone marrow transplantation nationallicence glioma nationallicence high grade nationallicence oligodendroglioma nationallicence thiotepa nationallicence Saarinen Ulla Children's Hospital, University of Helsinki, Helsinki, Finland aut Pihko Helena Children's Hospital, University of Helsinki, Helsinki, Finland aut Mäkipernaa Anne Children's Hospital, University of Helsinki, Helsinki, Finland aut Journal of Neuro-Oncology Kluwer Academic Publishers 9/1(1990-08-01), 57-61 0167-594X 9:1<57 1990 9 11060 https://doi.org/10.1007/BF00167069 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00167069 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Saarinen Ulla Children's Hospital, University of Helsinki, Helsinki, Finland aut NATIONALLICENCE 700 1- Pihko Helena Children's Hospital, University of Helsinki, Helsinki, Finland aut NATIONALLICENCE 700 1- Mäkipernaa Anne Children's Hospital, University of Helsinki, Helsinki, Finland aut NATIONALLICENCE 773 0- Journal of Neuro-Oncology Kluwer Academic Publishers 9/1(1990-08-01), 57-61 0167-594X 9:1<57 1990 9 11060 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer