caa a22 4500 465735215 CHVBK 20180323111753.0 cr unu---uuuuu 170327e19901201xx s 000 0 eng 10.1007/BF02341151 doi (NATIONALLICENCE)springer-10.1007/BF02341151 External beam radiotherapy for primary spinal cord tumors [Elektronische Daten] [Ha Chun, Rupert Schmidt-Ullrich, Aaron Wolfson, Oscar Tercilla, Robert Sagerman, Gerald King] Summary: Of 34 evaluated patients with primary spinal cord tumors, 32 were irradiated at our institutions between 1969 and 1983. The results are reported of 32 patients, 16 with ependymoma and 16 with astrocytoma, who were treated with postoperative external beam radiotherapy following biopsy or subtotal resection. Twenty-nine patients received 45-55 Gy megavoltage beam irradiation in five to six weeks, and the remaining three patients received less than 40 Gy. The minimum follow-up was five years. Five- and ten-year actuarial survival rates for the entire group of patients were 73% (22/30) and 50% (8/16), respectively, including three patients who were salvaged by surgery after radiotherapy failures. Corresponding five- and ten-year relapse-free survival rates were 60% (18/30) and 32% (6/19), respectively. Of the 29 patients who received more than 45 Gy, relapse-free survival at five years was 63% (17/27). Treatment failed in 13 patients, and all of those failures were within the irradiated portals. Patients with ependymomas have significantly better relapse free survival than those with astrocytomas, 80% vs. 40% (p < 0.05). There was a significant difference in survival between patients with tumors involving the cervical spine and those with tumors in the other locations, 45% vs. 89% (p < 0.05). There was no significant difference in survival between patients with cauda equina tumors and those with tumors of the spinal cord, 100% vs. 68% (p > 0.05). No radiotherapy-related neurological deficit was noted with a maximum 20 year follow-up. This study confirms that external beam radiotherapy is a safe and effective treatment modality for primary spinal cord tumors. Kluwer Academic Publishers, 1990 radiotherapy nationallicence spinal cord tumors nationallicence Chun Ha Department of Radiation Oncology, Medical College of Virginia, Box 58 - MCV Station, 23298, Richmond, VA aut Schmidt-Ullrich Rupert Department of Radiation Oncology, Medical College of Virginia, Box 58 - MCV Station, 23298, Richmond, VA aut Wolfson Aaron Department of Radiation Oncology, Medical College of Virginia, Box 58 - MCV Station, 23298, Richmond, VA aut Tercilla Oscar Department of Radiation Oncology, Medical College of Virginia, Box 58 - MCV Station, 23298, Richmond, VA aut Sagerman Robert Division of Radiation Oncology, State University of New York, Health Sciences Center, 13210, Syracuse, NY, USA aut King Gerald Division of Radiation Oncology, State University of New York, Health Sciences Center, 13210, Syracuse, NY, USA aut Journal of Neuro-Oncology Kluwer Academic Publishers 9/3(1990-12-01), 211-217 0167-594X 9:3<211 1990 9 11060 https://doi.org/10.1007/BF02341151 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02341151 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chun Ha Department of Radiation Oncology, Medical College of Virginia, Box 58 - MCV Station, 23298, Richmond, VA aut NATIONALLICENCE 700 1- Schmidt-Ullrich Rupert Department of Radiation Oncology, Medical College of Virginia, Box 58 - MCV Station, 23298, Richmond, VA aut NATIONALLICENCE 700 1- Wolfson Aaron Department of Radiation Oncology, Medical College of Virginia, Box 58 - MCV Station, 23298, Richmond, VA aut NATIONALLICENCE 700 1- Tercilla Oscar Department of Radiation Oncology, Medical College of Virginia, Box 58 - MCV Station, 23298, Richmond, VA aut NATIONALLICENCE 700 1- Sagerman Robert Division of Radiation Oncology, State University of New York, Health Sciences Center, 13210, Syracuse, NY, USA aut NATIONALLICENCE 700 1- King Gerald Division of Radiation Oncology, State University of New York, Health Sciences Center, 13210, Syracuse, NY, USA aut NATIONALLICENCE 773 0- Journal of Neuro-Oncology Kluwer Academic Publishers 9/3(1990-12-01), 211-217 0167-594X 9:3<211 1990 9 11060 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer