caa a22 4500 465735223 CHVBK 20180323111753.0 cr unu---uuuuu 170327e19901201xx s 000 0 eng 10.1007/BF02341154 doi (NATIONALLICENCE)springer-10.1007/BF02341154 Central nervous system neurocytoma and neuroblastoma in adults-report of eight cases [Elektronische Daten] [David Louis, Brooke Swearingen, Rita Linggood, G. Dickersin, Cynthia Kretschmar, Atul Bhan, E. Hedley-Whyte] Summary: The clinical features, pathologic findings and treatment courses of eight adults with central nervous system small-cell neuronal tumors were reviewed. Five patients had central neurocytomas, two patients central nervous system neuroblastomas, and one patient a neurocytoma-like spinal cord tumor. The neurocytomas were intraventricular, moderately cellular tumors with bland nuclei and perinuclear halos. Patients with neurocytoma were treated with surgery, radiation therapy, and/or chemotherapy, and have followed favorable clinical courses. The neuroblastomas were intraparenchymal, hypercellular tumors with necrosis and frequent mitoses. Patients with neuroblastomas were treated with surgery, radiation therapy and chemotherapy, with some clinical response, but overall poor survival. One of the two patients developed extracranial metastasis. The spinal cord tumor had histologic features of neurocytoma, and responded well to biopsy and radiation therapy. The cases are compared with the varieties of small-celled neuronal tumors described in the literature, and pathologic, histogenetic and treatment implications are discussed. Kluwer Academic Publishers, 1990 neuroblastoma nationallicence neurocytoma nationallicence central nervous system tumors nationallicence spinal cord tumor nationallicence Louis David Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut Swearingen Brooke Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut Linggood Rita Department of Radiation Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut Dickersin G. Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut Kretschmar Cynthia Department of Pediatrics, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut Bhan Atul Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut Hedley-Whyte E. Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut Journal of Neuro-Oncology Kluwer Academic Publishers 9/3(1990-12-01), 231-238 0167-594X 9:3<231 1990 9 11060 https://doi.org/10.1007/BF02341154 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02341154 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Louis David Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut NATIONALLICENCE 700 1- Swearingen Brooke Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut NATIONALLICENCE 700 1- Linggood Rita Department of Radiation Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut NATIONALLICENCE 700 1- Dickersin G. Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut NATIONALLICENCE 700 1- Kretschmar Cynthia Department of Pediatrics, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut NATIONALLICENCE 700 1- Bhan Atul Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut NATIONALLICENCE 700 1- Hedley-Whyte E. Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA aut NATIONALLICENCE 773 0- Journal of Neuro-Oncology Kluwer Academic Publishers 9/3(1990-12-01), 231-238 0167-594X 9:3<231 1990 9 11060 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer