caa a22 4500 465735347 CHVBK 20180323111753.0 cr unu---uuuuu 170327e19901001xx s 000 0 eng 10.1007/BF02427838 doi (NATIONALLICENCE)springer-10.1007/BF02427838 Primitive pineal tumor with retinoblastomatous and retinal/ciliary epithelial differentiation: an immunohistochemical study [Elektronische Daten] [Jack Raisanen, Hannes Vogel, Dikran Horoupian] A one year old boy was found to have a large tumor encompassing the pineal region and extending towards the third and lateral ventricles and quadrigeminal plate. The tumor was composed mostly of small, undifferentiated cells. Some small cells were arranged in Flexner-Wintersteiner rosettes and a few displayed fleurettes. The tumor contained immature cartilage and skeletal muscle and numerous clusters of pigmented epithelial-like cells which, histologically, resembled those found in melanotic neuroectodermal tumors of infancy (retinal anlage tumors) and retinal or ciliary epithelium. Immunologic stains demonstrated neurofilaments, synaptophysin and retinal S-antigen in some of the small cells and transthyretin in some of the epithelial-like cells. The findings indicate that certain primary pineal parenchymal tumors have features in common with tumors of the ocular medullary epithelium. Kluwer Academic Publishers, 1990 primitive pineal tumor nationallicence pineoblastoma nationallicence retinoblastoma nationallicence retinal anlage tumor nationallicence transthyretin nationallicence retinal S-antigen nationallicence Raisanen Jack Department of Pathology (Neuropathology), Stanford University School of Medicine, 94305, Stanford, CA, USA aut Vogel Hannes Department of Pathology (Neuropathology), Stanford University School of Medicine, 94305, Stanford, CA, USA aut Horoupian Dikran Department of Pathology (Neuropathology), Stanford University School of Medicine, 94305, Stanford, CA, USA aut Journal of Neuro-Oncology Kluwer Academic Publishers 9/2(1990-10-01), 165-170 0167-594X 9:2<165 1990 9 11060 https://doi.org/10.1007/BF02427838 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02427838 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Raisanen Jack Department of Pathology (Neuropathology), Stanford University School of Medicine, 94305, Stanford, CA, USA aut NATIONALLICENCE 700 1- Vogel Hannes Department of Pathology (Neuropathology), Stanford University School of Medicine, 94305, Stanford, CA, USA aut NATIONALLICENCE 700 1- Horoupian Dikran Department of Pathology (Neuropathology), Stanford University School of Medicine, 94305, Stanford, CA, USA aut NATIONALLICENCE 773 0- Journal of Neuro-Oncology Kluwer Academic Publishers 9/2(1990-10-01), 165-170 0167-594X 9:2<165 1990 9 11060 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer