caa a22 4500 465735517 CHVBK 20180323111753.0 cr unu---uuuuu 170327e19900201xx s 000 0 eng 10.1007/BF00182084 doi (NATIONALLICENCE)springer-10.1007/BF00182084 An immunocytochemical comparison of glial fibrillary acidic protein, S-100p and vimentin in human glial tumors [Elektronische Daten] [L. Nakopoulou, E. Kerezoudi, T. Thomaides, B. Litsios] Immunostaining patterns of glial fibrillary acidic protein (GFAP), S-100 protein (S-100p) and vimentin were studied using immunohistochemical techniques on 48 paraffin embedded glial tumors. GFAP was positive in all tumor cases except in two oligodendrogliomas. S-100p was found in most astroglial tumors and in half of the oligodendrogliomas. Vimentin was positive in many astrocytomas but in no oligodendrogliomas. Most astroglial tumors showed similar immunoreactivity for GFAP and S-100p. Fibrillary processes, however, showed stronger and more crisp staining with anti-GFAP than with anti-S-100p, whereas cell nuclei were labeled only for S-100p. Vimentin was localised mainly in juxtanuclear positions. In many astrocytomas with different degrees of malignancy co-expression of GFAP, S-100p and vimentin was found. The presence of GFAP and S-100p was not correlated with the degree of differentiation in astrocytomas. Vimentin was more positive in anaplastic astrocytomas but this finding was not statistically significant. It seems that GFAP is a superior marker to S-100p and vimentin in the identification of human gliomas. Kluwer Academic Publishers, 1990 glial fibrillary acidic protein (GFAP) nationallicence S-100 protein nationallicence vimentin nationallicence immunocytochemistry nationallicence glial tumors nationallicence Nakopoulou L. Department of Pathology, University of Athens, GR-11527, Athens, Greece aut Kerezoudi E. Department of Pathology, University of Athens, GR-11527, Athens, Greece aut Thomaides T. Department of Pathology, University of Athens, GR-11527, Athens, Greece aut Litsios B. Department of Pathology, University of Athens, GR-11527, Athens, Greece aut Journal of Neuro-Oncology Kluwer Academic Publishers 8/1(1990-02-01), 33-40 0167-594X 8:1<33 1990 8 11060 https://doi.org/10.1007/BF00182084 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00182084 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nakopoulou L. Department of Pathology, University of Athens, GR-11527, Athens, Greece aut NATIONALLICENCE 700 1- Kerezoudi E. Department of Pathology, University of Athens, GR-11527, Athens, Greece aut NATIONALLICENCE 700 1- Thomaides T. Department of Pathology, University of Athens, GR-11527, Athens, Greece aut NATIONALLICENCE 700 1- Litsios B. Department of Pathology, University of Athens, GR-11527, Athens, Greece aut NATIONALLICENCE 773 0- Journal of Neuro-Oncology Kluwer Academic Publishers 8/1(1990-02-01), 33-40 0167-594X 8:1<33 1990 8 11060 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer